Results 11 to 20 of about 10,197,473 (297)

Fibroblast growth factor receptors in breast cancer [PDF]

Tumor Biology, 2017
Fibroblast growth factor receptors are growth factor receptor tyrosine kinases, exerting their roles in embryogenesis, tissue homeostasis, and development of breast cancer.
Shuwei Wang, Zhongyang Ding
doaj   +5 more sources

FGFR1 (Fibroblast Growth Factor Receptor 1) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on FGFR1 (fibroblast growth factor receptor 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Huret, JL
core   +7 more sources

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis [PDF]

Cytokine & Growth Factor Reviews, 2005
Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert their pro-angiogenic activity by interacting with various endothelial cell surface receptors, including tyrosine kinase receptors, heparan-sulfate proteoglycans, and integrins.
PRESTA, Marco, DELL'ERA, Patrizia, MITOLA, Stefania Maria Filomena, MORONI, Emanuela, RONCA, Roberto, RUSNATI, Marco   +5 more
openaire   +5 more sources

Fibroblast Growth Factor Receptor Functions in Glioblastoma [PDF]

Cells, 2019
Glioblastoma is the most lethal brain cancer in adults, with no known cure. This cancer is characterized by a pronounced genetic heterogeneity, but aberrant activation of receptor tyrosine kinase signaling is among the most frequent molecular alterations
Ana Jimenez-Pascual, Florian A. Siebzehnrubl   +1 more
doaj   +4 more sources

Fibroblast growth factor 10 attenuates advanced liver fibrosis through hepatocyte fibroblast growth factor receptor 2 signalling [PDF]

Clinical and Translational Medicine
Background Metabolic dysfunction–associated steatotic liver disease (MASLD) and advanced fibrotic stages are significant contributors to cirrhosis and liver‐related mortality, yet no therapies directly target fibrosis in the later stages of the disease ...
Xuanxin Yang, Qingqing Dong, Jiaying Ma, Yawei Yan, Shuangyan Peng, Qiqi Wu, Huan Wang, Tingting Zhang, Panyu Zhang, Zelong Jiang, Chao Lu, Le Li, Xinyi You, Yuandong Xu, Joshua Banda, Zhixiang Mu, Minghua Zheng, Xiaokun Li, Qi Hui, Bingjie Yu, Xiaojie Wang   +20 more
doaj   +2 more sources

Conceptualization of fibroblast growth factor receptor 1 targeting nanomedicines [PDF]

Exploration of Targeted Anti-tumor Therapy
Fibroblast growth factor receptor 1 (FGFR1) is crucial in the progression of various cancers, participating in the processes of cell proliferation, survival, and differentiation. FGFR1 plays a role in the resistance to immune checkpoint inhibitors (ICIs)
Yilin Ma, Mengqin Guo, Yang Liu, Zhengwei Huang   +3 more
doaj   +2 more sources

Design and characteristics of cytotoxic fibroblast growth factor 1 conjugate for fibroblast growth factor receptor-targeted cancer therapy

Drug Design, Development and Therapy, 2016
Anna Szlachcic, Malgorzata Zakrzewska, Michal Lobocki, Piotr Jakimowicz, Jacek Otlewski Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, Wroclaw, Poland Abstract: Fibroblast growth factor receptors (FGFRs) are ...
Szlachcic A, Zakrzewska M, Lobocki M, Jakimowicz P, Otlewski J   +4 more
doaj   +1 more source

Basic fibroblast growth factor and fibroblast growth factor receptors in adult olfactory epithelium

Brain Research, 2001
Basic fibroblast growth factor (FGF2) stimulates proliferation of the globose basal cells, the neuronal precursor in the olfactory epithelium. The present study investigates the expression of basic fibroblast growth factor and fibroblast growth factor receptors in the adult olfactory epithelium.
Hsu, P, Yu, F, Feron, F, Pickles, JO, Sneesby, K, Mackay-Sim, A   +5 more
openaire   +7 more sources

Protein kinase B inhibitors enhance the sensitivity of translocated promoter region–fibroblast growth factor receptor 1 cells to fibroblast growth factor receptor 1 inhibitor-induced apoptosis [PDF]

Journal of International Medical Research
Objective Fibroblast growth factor receptor 1 (FGFR1) inhibitors are considered effective for treating 8p11 myeloproliferative syndrome. However, targeting FGFR1 alone may be inadequate for patients with translocated promoter region (TPR)–FGFR1 ...
Mengyao Lv, Wenbing Shangguan, Qian Zhao, Yan Li, Quan Zhao, Feng Li   +5 more
doaj   +2 more sources

Evocalcet with vitamin D receptor activator treatment for secondary hyperparathyroidism

PLoS ONE, 2022
This ad hoc analysis of a previously conducted phase 3 head-to-head comparison study of evocalcet and cinacalcet in secondary hyperparathyroidism patients undergoing maintenance hemodialysis evaluated the efficacy and safety of combined once-daily oral ...
Takashi Shigematsu, Shinji Asada, Yuichi Endo, Takehisa Kawata, Masafumi Fukagawa, Tadao Akizawa   +5 more
doaj   +2 more sources