Results 171 to 180 of about 5,605 (194)
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Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health, 2012
An excessive maternal systemic inflammatory response to pregnancy, as well as an imbalance between circulating angiogenic factors and their antagonists plays a central role in the pathogenesis of preeclampsia. The complement system, as part of innate immunity, is fundamental to the host's immune defense against microbial pathogens, apoptotic and ...
A, Molvarec +6 more
openaire +2 more sources
An excessive maternal systemic inflammatory response to pregnancy, as well as an imbalance between circulating angiogenic factors and their antagonists plays a central role in the pathogenesis of preeclampsia. The complement system, as part of innate immunity, is fundamental to the host's immune defense against microbial pathogens, apoptotic and ...
A, Molvarec +6 more
openaire +2 more sources
Can ficolin‐2 (L‐ficolin) insufficiency be established by a single serum protein measurement?
International Journal of Immunogenetics, 2015SummarySerum ficolin‐2 was measured in multiple (2‐27) samples from 68 paediatric sepsis patients. Fourteen individuals (21%) gave values that included a change in status from ‘normal’ to ‘insufficient’ or vice versa. Therefore, if possible, ficolin‐2 concentration should be determined in samples obtained when a disease is inactive.
D C, Kilpatrick +6 more
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Molecular Immunology, 2009
We previously reported an association between relative L-ficolin deficiency and recurrent respiratory infections co-existing with allergic disorders in children. To confirm and extend this preliminary finding, we performed a prospective study on children of a similar age (mean 8.9 years) designed to establish whether the principal relationship was with
Maciej Cedzynski +2 more
exaly +3 more sources
We previously reported an association between relative L-ficolin deficiency and recurrent respiratory infections co-existing with allergic disorders in children. To confirm and extend this preliminary finding, we performed a prospective study on children of a similar age (mean 8.9 years) designed to establish whether the principal relationship was with
Maciej Cedzynski +2 more
exaly +3 more sources
The lectin complement pathway and Ficolin-2 in patients with necrotizing soft tissue infection
The Journal of Immunology, 2016Abstract Background Mannose-binding lectin (MBL) and ficolins are pattern recognition molecules (PRMs) that play an important role during infection through activation of the lectin complement pathway. We assessed whether blood concentrations of the PRMs were associated with mortality in patients with ...
Marco Bo Hansen +7 more
openaire +1 more source
Molecular Immunology, 2017
Background: Inflammatory mechanisms may be involved in atherosclerotic plaque rupture. By using a novel histology-based method to quantify plaque instability here we assess whether the activation of the lectin complement pathway (LP), a major inflammation arm, could represent an index of plaque instability.
Fumagalli, Stefano +9 more
openaire +2 more sources
Background: Inflammatory mechanisms may be involved in atherosclerotic plaque rupture. By using a novel histology-based method to quantify plaque instability here we assess whether the activation of the lectin complement pathway (LP), a major inflammation arm, could represent an index of plaque instability.
Fumagalli, Stefano +9 more
openaire +2 more sources
Ficolin-2 and FCN2 in patients with systemic inflammation
Molecular Immunology, 2011L. Munthe-Fog +3 more
openaire +1 more source