Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patients [PDF]
, 2018 Background: Sepsis is a life-threatening illness with a challenging diagnosis. Current serum biomarkers are not sensitive enough for diagnosis. With the aim of finding proteins associated with sepsis, serum protein profile was compared between patients ...
Astigarraga Aguirre, María Iciar +7 more
core +3 more sources
Scientific Reports, 2020 Active ingredients derived from natural sources are widely utilized in many industries. Cosmetic active ingredients are largely derived from various plants.
Kyung-Ha Lee, Jeong Pyo Lee, Wanil Kim
doaj +1 more source
Mesenchymal stem cells express epidermal markers in an in vitro reconstructed human skin model
Frontiers in Cell and Developmental Biology, 2023 Introduction: In skin traumas, such as burns, epidermal homeostasis is affected, often requiring clinical approaches. Different therapeutic strategies can be used including transplantation, besides the use of synthetic or natural materials with ...
Jeniffer Farias Dos Santos +6 more
doaj +1 more source
Genetic and epigenetic studies of atopic dermatitis [PDF]
, 2016 Additional file 2: References.
Donald Y. M. Leung, Lianghua Bin
core +3 more sources
Expression of Skin Barrier Protein Filaggrin in Skin Diseases without Atopic Dermatitis
Journal of Biosciences and Medicines, 2018 The epidermis represents an essential barrier versus a broad range of exogenous stimuli. To form a functional epidermis, keratinocytes express filaggrin which plays a vital role in atopic dermatitis. However the relationship between filaggrin and other skin diseases remains unknown.
Yang Zhang +3 more
openaire +2 more sources
CARD14 gain-of-function mutation alone is sufficient to drive IL-23/IL-17-mediated psoriasiform skin inflammation in vivo [PDF]
, 2018 Rare autosomal dominant mutations in the gene encoding the keratinocyte signaling molecule, Caspase Recruitment Domain-Containing Protein 14 (CARD14), have been associated with an increased susceptibility to psoriasis but the physiological impact of ...
Cheng, Phil +11 more
core +1 more source
Exosomes in the nose induce immune cell trafficking and harbour an altered protein cargo in chronic airway inflammation [PDF]
, 2016 Background: Exosomes are nano-sized extracellular vesicles participating in cell-to-cell communication both in health and disease. However, the knowledge about the functions and molecular composition of exosomes in the upper airways is limited.
GHO, YONG SONG +7 more
core +4 more sources
Cells, 2022 The lingual mucosa in birds is covered with two specific types of multilayered epithelia, i.e., the para- and orthokeratinized epithelium, that differ structurally and functionally. Comprehensive information on proteins synthesized in keratinocyte during
Kinga Skieresz-Szewczyk +2 more
doaj +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Protective Effects of Triphala on Dermal Fibroblasts and Human Keratinocytes. [PDF]
PLoS ONE, 2016 Human skin is body's vital organ constantly exposed to abiotic oxidative stress. This can have deleterious effects on skin such as darkening, skin damage, and aging.
Sandeep R Varma +6 more
doaj +1 more source