Results 31 to 40 of about 6,491,911 (254)
Human filaggrin monomer does not seem to be a proteasome target
Experimental Dermatology, 2023 Absence of a functional proteasome in the suprabasal layers of the epidermis is responsible for keratosis linearis with ichthyosis congenital and sclerosing keratoderma syndrome.
J. Briot +5 more
semanticscholar +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2022 Significance Filaggrin (FLG) is one of the structural proteins for skin barrier function. Reduced FLG expression is implicated in the pathogenesis of inflammatory skin diseases, such as atopic dermatitis and psoriasis. However, it remains unclear how FLG
S. Ahn +5 more
semanticscholar +1 more source
Barrier proteins and eosinophilic esophagitis in children: the role of E-cadherin and filaggrin
Allergologia et Immunopathologia, 2022 This study aimed to assess the protein expression of E-cadherin and filaggrin (FLG) in the oesophagus of paediatric and adolescent patients diagnosed with eosinophilic esophagitis (EoE). It is a cross-sectional study conducted with 24 patients with EoE and 17 control patients, from June 2015 to June 2018.
Erica Rezende +6 more
openaire +2 more sources
Modern View on the Role of Epidermal Barrier in Atopic Phenotype Development in Children
Вопросы современной педиатрии, 2020 Epidermal barrier is one is one of the most important structures of the skin, it performs protective function, ensure internal environment constancy by selective ions and molecules transport and by transepidermal water loss regulation.
Nikolay N. Murashkin +5 more
doaj +1 more source
Gut, 2022 Objective Disruption of the epithelial barrier plays an essential role in developing eosinophilic oesophagitis (EoE), a disease defined by type 2 helper T cell (Th2)-mediated food-associated and aeroallergen-associated chronic inflammation.
Tanay Kaymak +10 more
semanticscholar +1 more source
Expression of keratins, epidermal proteins and inflammatory cells in superficial pemphigus dogs [PDF]
Bulgarian Journal of Veterinary Medicine, 2018 Superficial pemphigus in dogs is an autoimmune skin disorder. The disease is characterised by the binding of auto-antibodies to desmosomal molecules including desmocollin-1, a major auto-antigen in dogs.
S. Theerawatanasirikul +3 more
doaj +1 more source
The effect of long-term cigarette smoking on selected skin barrier proteins and lipids
Scientific Reports, 2023 The negative impact of cigarette smoking on the skin includes accelerated aging, pigmentation disorders, and impaired wound healing, but its effect on the skin barrier is not completely understood.
Kristýna Hergesell +5 more
semanticscholar +1 more source
THE ROLE OF GENETIC POLYMORPHISM OF THE FILAGGRIN PROTEIN WITH ATOPIC MARCH PROGRESSION IN CHILDREN
InterConf, 2021 The aim of the study. To determine the role of genetic polymorphism in the filaggrin gene R501XAA and 2282de4AA at atopic march progression in children. Materials and methods. 111 children aged 3 to 12 years with atopic dermatitis were selected and examined.
Stoieva, T. V. +5 more
openaire +2 more sources
Physicochemical study of a synthetic peptide belonging to human filaggrin protein [PDF]
Le Journal de Physique IV, 2001 In the present work the physicochemical characterization of the (306-324) synthetic peptide sequence from human fiiaggrin protein and its palmitoilated derivative was carried out. Monomolecular layers of dipalmitoilphosphatidilcholine (DPPC) were used to study lipidtpeptide interactions.
T. Pérez +4 more
openaire +1 more source
Associations of filaggrin gene loss-of-function variants and human papillomavirus-related cancer and pre-cancer in Danish adults. [PDF]
PLoS ONE, 2014 Filaggrin proteins are expressed in the skin, oral cavity, oesophagus, and cervical mucose. Loss-of-function mutations in the filaggrin gene (FLG) reduce filaggrin expression and cause an impaired skin barrier function.
Tea Skaaby +9 more
doaj +1 more source