Results 11 to 20 of about 6,491,911 (254)
Tuning the Cell-Free Protein Synthesis System for Biomanufacturing of Monomeric Human Filaggrin [PDF]
Frontiers in Bioengineering and Biotechnology, 2020 The modern cell-free protein synthesis (CFPS) system is expanding the opportunity of cell-free biomanufacturing as a versatile platform for synthesizing various therapeutic proteins.
Jeehye Kim +6 more
doaj +4 more sources
Refined Immunochemical Characterization in Healthy Dog Skin of the Epidermal Cornification Proteins, Filaggrin, and Corneodesmosin [PDF]
Journal of Histochemistry & Cytochemistry, 2018 Filaggrin (FLG) and corneodesmosin (CDSN) are two key proteins of the human epidermis. FLG loss-of-function mutations are the strongest genetic risk factors for human atopic dermatitis.
D. Pin +9 more
semanticscholar +4 more sources
Update on canine filaggrin: a review
Veterinary Quarterly, 2020 Human filaggrin (FLG) plays a key role in epidermal barrier function, and loss-of-function mutations of its gene are primarily responsible for the development of human atopic dermatitis (AD).
Daniel Combarros +2 more
doaj +2 more sources
Skin barrier in atopic dermatitis: beyond filaggrin [PDF]
Anais Brasileiros de Dermatologia, 2016 : Atopic dermatitis is a chronic inflammatory skin disease with a complex pathogenesis, where changes in skin barrier and imbalance of the immune system are relevant factors.
Mariana Colombini Zaniboni +3 more
doaj +2 more sources
Frontiers in Immunology, 2021 Atopic dermatitis (AD) is a chronic relapsing pruritic disease encompassing skin inflammation and barrier dysfunction. House dust mites are key allergens that augment the development of atopic dermatitis.
Hyang Jeon +9 more
doaj +2 more sources
Studies Using Antibodies against Filaggrin and Filaggrin 2 in Canine Normal and Atopic Skin Biopsies
AnimalsSimple Summary In people, skin allergies to environmental factors have been linked to abnormalities in the skin itself. One of these abnormalities in people is a lower amount of a family of skin proteins called filaggrins.
Rosanna Marsella +2 more
exaly +2 more sources
Clinical, Cosmetic and Investigational DermatologyYong-Han Cho,1 Ji-Woo Kim,1 Nari Kim,1 Hee-Sik Kim,1 Jun-Hwan Jang,1 Jun-Tae Bae,1 Wanil Kim2 1J2K-Metabiome, J2KBIO, Cheongju, Republic of Korea; 2Department of Biochemistry, Department of Convergence Medical Science, and Institute of Medical Science ...
Cho YH +6 more
doaj +2 more sources
Comparative genomics reveals conservation of filaggrin and loss of caspase‐14 in dolphins
Experimental Dermatology, 2015 The expression of filaggrin and its stepwise proteolytic degradation are critical events in the terminal differentiation of epidermal keratinocytes and in the formation of the skin barrier to the environment.
Veronika Mlitz +2 more
exaly +2 more sources
Protective Effect of Peony (Paeonia ostii) Flower Extract Against Tape Stripping-Induced Skin Barrier Impairment in Mice [PDF]
MoleculesBackground: Skin barrier dysfunction leads to increased transepidermal water loss (TEWL), inflammation, and compromised skin protection. While Paeonia ostii (peony) flowers are recognized in traditional Chinese medicine for their reducing melanin ...
Ruiying Yang +7 more
doaj +2 more sources
Journal of the European Academy of Dermatology and Venereology, 2015 Raquel Leão Orfali +2 more
exaly +2 more sources