Results 101 to 110 of about 8,401 (235)

Complete protection of the BALB/c and C57BL/6J mice against Ebola and Marburg virus lethal challenges by pan-filovirus T-cell epigraph vaccine.

open access: yesPLoS Pathogens, 2019
There are a number of vaccine candidates under development against a small number of the most common outbreak filoviruses all employing the virus glycoprotein (GP) as the vaccine immunogen.
Md Niaz Rahim   +11 more
doaj   +1 more source

Diabetes as a tracer condition in international benchmarking of health systems.

open access: yes, 2006
OBJECTIVE: To assess the performance of health systems using diabetes as a tracer condition. RESEARCH DESIGN AND METHODS: We generated a measure of "case-fatality" among young people with diabetes using the mortality-to-incidence ratio (M/I ratio) for 29
Bain, Chris, McKee, Martin, Nolte, Ellen
core   +1 more source

Identifizierung und Charakterisierung der Interaktion von Marburg-Virus VP30 mit den zellulären Proteinen PIAS1, PIAS2 und SETDB1 [PDF]

open access: yes, 2018
Marburg-Virus (MARV) und Ebola-Virus (EBOV), Mitglieder der Virusfamilie der Filoviridae, lösen schwere, oft tödlich verlaufende Erkrankungen im Menschen und nicht-menschlichen Primaten aus.
Klüver, Michael
core   +1 more source

Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors

open access: yesCell Reports, 2018
Summary: Some monoclonal antibodies (mAbs) recovered from survivors of filovirus infections can protect against infection. It is currently unknown whether natural infection also induces some antibodies with the capacity for antibody-dependent enhancement
Natalia A. Kuzmina   +10 more
doaj  

Evasion of the Interferon-Mediated Antiviral Response by Filoviruses

open access: yesViruses, 2010
The members of the filoviruses are recognized as some of the most lethal viruses affecting human and non-human primates. The only two genera of the Filoviridae family, Marburg virus (MARV) and Ebola virus (EBOV), comprise the main etiologic agents of ...
Washington B. Cárdenas
doaj   +1 more source

Ebola et Marburg : les hommes contre-attaquent [PDF]

open access: yes, 2006
La fréquence des épidémies de fièvres hémorragiques à virus Ebola ou Marburg constatée en Afrique Centrale est en augmentation depuis une dizaine d’années.
Alazard-Dany, Nathalie   +2 more
core  

Clinical Documentation and Data Transfer from Ebola and Marburg Virus Disease Wards in Outbreak Settings: Health Care Workers’ Experiences and Preferences

open access: yesViruses, 2014
Understanding human filovirus hemorrhagic fever (FHF) clinical manifestations and evaluating treatment strategies require the collection of clinical data in outbreak settings, where clinical documentation has been limited.
Silja Bühler   +3 more
doaj   +1 more source

Deep Sequencing Identifies Noncanonical Editing of Ebola and Marburg Virus RNAs in Infected Cells

open access: yesmBio, 2014
Deep sequencing of RNAs produced by Zaire ebolavirus (EBOV) or the Angola strain of Marburgvirus (MARV-Ang) identified novel viral and cellular mechanisms that diversify the coding and noncoding sequences of viral mRNAs and genomic RNAs.
Reed S. Shabman   +7 more
doaj   +1 more source

Genetics-Based Classification of Filoviruses Calls for Expanded Sampling of Genomic Sequences

open access: yesViruses, 2012
We have recently developed a computational approach for hierarchical, genome-based classification of viruses of a family (DEmARC). In DEmARC, virus clusters are delimited objectively by devising a universal family-wide threshold on intra-cluster genetic ...
Alexander E. Gorbalenya, Chris Lauber
doaj   +1 more source

Home - About - Disclaimer - Privacy