Results 71 to 80 of about 5,486 (195)

Obtaining and Immunologic Characterization of Filoviruses Recombinant Proteins VP40 and NP

Проблемы особо опасных инфекций, 2010
Full-size genes coding matrix proteins VP40 of Ebola virus (VE) and Marburg virus (VM) and nucleoprotein (NP) of VE were cloned. These genes expression in Escherichia coli and purification of their products by affinity chromatography using Ni-NTA agarose
A. V. Ivanova, E. I. Kazachinskaya, A. V. Kachko, E. L. Subbotina, A. V. Sorokin, I. A. Razumov, S. V. Neteosov, V. B. Loktev   +7 more
doaj   +1 more source

Inhibition of Ebola Virus by Anti-Ebola miRNAs in silico

Journal of Infection in Developing Countries, 2016
Introduction: MicroRNAs (miRNAs) are small, noncoding RNA molecules that regulate transcriptional and posttranscriptional gene regulation of the organisms. miRNA provides immune defense when the body is faced with challenges intracellular agents.
Zhabiz Golkar, Roshan Battaria, Donald G Pace, Omar Bagasra   +3 more
doaj   +1 more source

Marburg Virus Reverse Genetics Systems

Viruses, 2016
The highly pathogenic Marburg virus (MARV) is a member of the Filoviridae family and belongs to the group of nonsegmented negative-strand RNA viruses.
Kristina Maria Schmidt, Elke Mühlberger
doaj   +1 more source

Shedding Light on Filovirus Infection with High-Content Imaging

Viruses, 2012
Microscopy has been instrumental in the discovery and characterization of microorganisms. Major advances in high-throughput fluorescence microscopy and automated, high-content image analysis tools are paving the way to the systematic and quantitative ...
Rekha G. Panchal, Gianluca Pegoraro, Sina Bavari   +2 more
doaj   +1 more source

Multiplex Nucleic Acid Suspension Bead Arrays for Detection and Subtyping of Filoviruses [PDF]

, 2015
Cecilia Bergqvist, Petra Holmström, Gunnel Lindegren, Nina Lagerqvist, Mikael Leijon, Kerstin I. Falk   +5 more
openalex   +1 more source

Seroprevalence of Antibodies to Filoviruses with Outbreak Potential in Sub-Saharan Africa: A Systematic Review to Inform Vaccine Development and Deployment

Vaccines
Background/Objectives: Orthoebolaviruses and orthomarburgviruses are filoviruses that can cause viral hemorrhagic fever and significant morbidity and mortality in humans.
Christopher S. Semancik, Hilary S. Whitworth, Matt A. Price, Heejin Yun, Thomas S. Postler, Marija Zaric, Andrew Kilianski, Christopher L. Cooper, Monica Kuteesa, Sandhya Talasila, Nina Malkevich, Swati B. Gupta, Suzanna C. Francis   +12 more
doaj   +1 more source

A Diacylglycerol Kinase Inhibitor, R-59-022, Blocks Filovirus Internalization in Host Cells

Viruses, 2019
Filoviruses, such as Ebola virus (EBOV) and Marburg virus, are causative agents of unpredictable outbreaks of severe hemorrhagic fevers in humans and non-human primates.
Corina M. Stewart, Stephanie S. Dorion, Marie A. F. Ottenbrite, Nicholas D. LeBlond, Tyler K. T. Smith, Shirley Qiu, Morgan D. Fullerton, Darwyn Kobasa, Marceline Côté   +8 more
doaj   +1 more source

Exploring the evolution of filoviruses in vitro [PDF]

, 2014
Laura E. Avena, Kendra J. Alfson, Michael W. Beadles, Anthony Griffiths   +3 more
openalex   +1 more source

Laboratory detection and diagnosis of filoviruses

Virologica Sinica, 2011
Ebola virus (EBOV) and Marburg virus (MARV), belonging to the Filoviridae family, emerged four decades ago and caused severe viral hemorrhagic fever in human and other primates. As high as 50-90% mortality, filoviruses can cause significant threats to public health.
Yun-peng, Wang, Xian-en, Zhang, Hong-ping, Wei   +2 more
openaire   +3 more sources

Updates in diagnosis and management of Ebola hemorrhagic fever

Journal of Research in Medical Sciences, 2016
Ebola hemorrhagic fever is a lethal viral disease transmitted by contact with infected people and animals. Ebola infection represents a worldwide health threat causing enormous mortality rates and fatal epidemics. Major concern is pilgrimage seasons with
Salah Mohamed El Sayed, Ali A Abdelrahman, Hani Adnan Ozbak, Hassan Abdullah Hemeg, Ali Mohammed Kheyami, Nasser Rezk, Mohamed Baioumy El-Ghoul, Manal Mohamed Helmy Nabo, Yasser Mohamed Fathy   +8 more
doaj   +1 more source