Results 91 to 100 of about 4,417 (197)

Production of yeast cell wall polysaccharides‐β‐glucan and chitin by using food waste substrates: Biosynthesis, production, extraction, and purification methods

Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 3, May 2025.
Abstract Food waste causes significant environmental and economic challenges worldwide, prompting many nations to prioritize its reduction and recycling. As a nutrient‐rich material containing vitamins, proteins, and carbohydrates, it serves as a promising substrate for the cultivation of single‐cell microorganisms like yeast.
Deniz Günal‐Köroğlu, Gulsah Karabulut, Fariddudin Mohammadian, Aslı Can Karaca, Esra Capanoglu, Tuba Esatbeyoglu   +5 more
wiley   +1 more source

Candida kefyr in Kuwait: Prevalence, antifungal drug susceptibility and genotypic heterogeneity.

PLoS ONE, 2020
ObjectiveCandida kefyr causes invasive candidiasis in immunocompromised patients, particularly among those with oncohematological diseases. This study determined the prevalence of C.
Suhail Ahmad, Ziauddin Khan, Noura Al-Sweih, Wadha Alfouzan, Leena Joseph, Mohammad Asadzadeh   +5 more
doaj   +1 more source

Clade distribution of Candida auris in South Africa using whole genome sequencing of clinical and environmental isolates

Emerging Microbes and Infections, 2021
In South Africa, Candida auris was the third most common cause of candidemia in 2016–2017. We performed single nucleotide polymorphism (SNP) genome-wide analysis of 115 C.
Serisha D. Naicker, Tsidiso G. Maphanga, Nancy A. Chow, Mushal Allam, Stanford Kwenda, Arshad Ismail, Nelesh P. Govender   +6 more
doaj   +1 more source

Humanized Candida and NanoBiT Assays Expedite Discovery of Bdf1 Bromodomain Inhibitors With Antifungal Potential

Advanced Science, Volume 12, Issue 10, March 13, 2025.
The fungal BET protein Bdf1 is a potential antifungal target in pathogenic Candida species requiring the inhibition of both its bromodomains. Humanized Candida strains and NanoBiT complementation assays developed to evaluate on‐target antifungal efficacy expedite the discovery of Bdf1 bromodomain inhibitors with antifungal potential, supporting BET ...
Kaiyao Wei, Marie Arlotto, Justin M. Overhulse, Tuan‐Anh Dinh, Yingsheng Zhou, Nathan J. Dupper, Jiayi Yang, Boris A. Kashemirov, Hasan Dawi, Cécile Garnaud, Gaëlle Bourgine, Flore Mietton, Morgane Champleboux, Amédé Larabi, Yordan Hayat, Rose‐Laure Indorato, Marjolaine Noirclerc‐Savoye, Dimitrios Skoufias, Muriel Cornet, Gwenaël Rabut, Charles E. McKenna, Carlo Petosa, Jérôme Govin   +22 more
wiley   +1 more source

Suppressed Protein Translation Caused by MSP‐8 Deficiency Determines Fungal Multidrug Resistance with Fitness Cost

Advanced Science, Volume 12, Issue 6, February 10, 2025.
This study identifies msp‐8 as a novel multidrug‐resistance gene encoding a helicase in fungi, and reveals a previously unrecognized resistance mechanism. Dysfunction of MSP‐8 disrupts translation homeostasis, leading to reductions in intracellular ketoconazolelevels, membrane‐bound amphotericin B contents, and reactive oxygen species.
Mi Zhou, Pengju Yu, Chengcheng Hu, Wenxia Fang, Cheng Jin, Shaojie Li, Xianyun Sun   +6 more
wiley   +1 more source

Cloning of the Candida albicans homolog of Saccharomyces cerevisiae GSC1/FKS1 and its involvement in beta-1,3-glucan synthesis [PDF]

Journal of Bacteriology, 1997
Saccharomyces cerevisiae GSC1 (also called FKS1) and GSC2 (also called FKS2) have been identified as the genes for putative catalytic subunits of beta-1,3-glucan synthase. We have cloned three Candida albicans genes, GSC1, GSL1, and GSL2, that have significant sequence homologies with S. cerevisiae GSC1/FKS1, GSC2/FKS2, and the recently identified FKSA
T, Mio, M, Adachi-Shimizu, Y, Tachibana, H, Tabuchi, S B, Inoue, T, Yabe, T, Yamada-Okabe, M, Arisawa, T, Watanabe, H, Yamada-Okabe   +9 more
openaire   +2 more sources

Yeast species-specific, differential inhibition of β-1,3-glucan synthesis by poacic acid and caspofungin

The Cell Surface, 2018
The rise of widespread antifungal resistance fuels the need to explore new classes of inhibitory molecules as potential novel inhibitors. Recently a plant natural product poacic acid (PA) was shown to inhibit β-1,3-glucan synthesis, and to have ...
Keunsook K. Lee, Karen Kubo, Jehan Abdelmoneim Abdelaziz, Iain Cunningham, Alessandra de Silva Dantas, Xiaolin Chen, Hiroki Okada, Yoshikazu Ohya, Neil A.R. Gow   +8 more
doaj   +1 more source

Candida glabrata : a review of its features and resistance [PDF]

, 2014
Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous overgrowth to bloodstream infections.
A Chakrabarti, A Chakrabarti, A Kalkanci, A Kramer, A Peñas De Las, A Roetzer, A Roetzer, A Roetzer, A Roetzer, A Thierry, AA Almeida de, AL Colombo, AM Calcagno, AM Nicola, AW Segal, B Dujon, B Guo, B Klempp-Selb, BB Magee, BD Alexander, BP Cormack, C Lass-Flörl, C Marcos-Arias, C. F. Rodrigues, CJ Seneviratne, CS Kaufmann, CS Lim, CT Hittinger, CY Lin, D Dyk van, D Wilson, DA Stead, DC Sheppard, DJ Klionsky, DJ Klionsky, DM Kuhn, DR Reagan, EA Kraneveld, EJ Helmerhorst, EJ Helmerhorst, EK Bethea, EM Kojic, F Bambeke Van, F Barchiesi, F Hasan, FC Odds, FG Oppenheim, FG Oppenheim, G Butler, G Butler, G Luo, G Luo, G Ramage, G Ramage, GM Cox, GR Thompson 3rd, H Muller, H Tsai, H Urk Van, H Wisplinghoff, HM Bandara, HT Taff, I Castaño, I Iraqui, J Chandra, J Chandra, J Kim, J Lee, JA Hagerty, JA Jayatilake, JA Noble, JA Vazquez, JA Vazquez, JCO Sardi, JE Bennett, JH Shin, JL Vincent, JP Vermitsky, JR Blankenship, K Gulshan, K Lewis, K Lewis, K Seider, K Ueno, KE Caudle, KH Chen, KH Wolfe, KJ Verstrepen, KW Henry, L Vale-Silva, LP Samaranayake, LP Samaranayake, M Bassetti, M Edgerton, M Negri, M Niimi, M Niimi, M Riera, M Sikora, M Tscherner, M. Henriques, MA Al-Fattani, MA Pfaller, MA Pfaller, MA Pfaller, MC Arendrup, MC Lorenz, MD LaFleur, MD Lafleur, MN Rai, N Berila, NK Tamura, O Bader, P Gutiérrez-Escribano, P Perumal, P Shahi, P Sundstrom, P Uppuluri, P Vandeputte, P Vandeputte, PL Fidel Jr, PW Groot De, R Domergue, R Kaur, R Kaur, R Kaur, R Rajendran, RA Akins, RA Calderone, RD Cannon, RK Shields, S Brunke, S Brunke, S Farahyar, S Ferrari, S Ferrari, S Hawser, S Paul, S Silva, S Silva, S Silva, S Silva, S Silva, S. Silva, SC Halliwell, SP Hawser, SY Ruan, T Miyazaki, T Saijo, TFC Mah, V Krcmery, V Krcmery, V Mohan das, Y Nakagawa, Z Jandric, Z Xie   +155 more
core   +1 more source

Virulence and resistance factors of Nakaseomyces glabratus (formerly known as Candida glabrata) in Europe: A systematic review

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 2, Page 377-388, February 2025.
Nakaseomyces glabratus (formerly known as Candida glabrata) is an endogenous opportunistic pathogen that causes various clinical manifestations, ranging from mucocutaneous overgrowth to bloodstream infections. This review aims to summarize the biology, epidemiology and pathology of N.
Carmen Rodríguez‐Cerdeira, Rodolfo Pinto‐Almazán, Ditte M. L. Saunte, R. Hay, Jacek C. Szepietowski, Gabriela Moreno‐Coutiño, Mihael Skerlev, Asja Prohic, Erick Martínez‐Herrera   +8 more
wiley   +1 more source

Disseminated Candidiasis Caused by Candida albicans with Amino Acid Substitutions in Fks1 at Position Ser645 Cannot Be Successfully Treated with Micafungin [PDF]

Antimicrobial Agents and Chemotherapy, 2011
ABSTRACT The clinical utility of the echinocandins is potentially compromised by the emergence of drug resistance. We investigated whether Candida albicans with amino acid substitutions at position Ser645 in Fks1 can be treated with either a conventional or an elevated dosage of micafungin. We studied
Slater, J. L., Howard, S. J., Sharp, A., Goodwin, J., Gregson, L. M., Alastruey-Izquierdo, A., Arendrup, M. C., Warn, P. A., Perlin, D. S., Hope, W. W.   +9 more
openaire   +3 more sources