Results 71 to 80 of about 3,923 (195)
Two echinocandin-resistant Candida glabrata FKS mutants from South Africa
Medical Mycology Case Reports, 2016 Echinocandins are recommended as first-line agents to treat invasive infections caused by Candida glabrata since this organism is inherently less susceptible to azoles. However, resistance to echinocandins has been described in C.
Serisha D. Naicker +6 more
doaj +1 more source
Journal of Fungi, 2023 Echinocandins, used for the prevention and treatment of invasive fungal infections, have led to a rise in breakthrough infections caused by resistant Candida species.
Laura N. Silva +8 more
doaj +1 more source
International Journal of Microbiology, Volume 2026, Issue 1, 2026.Candida species are well‐known for their capacity to cause a broad range of infections in humans. Invasive and device‐related infections caused by Candida albicans and non‐albicans contribute to a relatively high mortality rate, thereby becoming a major public health concern around the world.
Evita Mayasari +2 more
wiley +1 more source
Resistance in Candida albicans: exploring the cell wall barrier by proteomics [PDF]
, 2015 The incidence of candidiasis has dramatically increased and bloodstream infections due to different species of Candida are becoming a prime cause of morbidity and mortality in different types of immunocompromised patients.
Angiolella, Letizia +2 more
core +1 more source
Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors [PDF]
Antimicrobial Agents and Chemotherapy, 1997 Pneumocandins and echinocandins are fungicidal antibiotics, currently in clinical development, that inhibit 1,3-beta-D-glucan synthase (GS) in several human fungal pathogens. We have identified a gene from the diploid organism Candida albicans that encodes a target of these inhibitors.
C M, Douglas +11 more
openaire +2 more sources
Frontiers in Cellular and Infection Microbiology, 2021 BackgroundThe incidence of invasive candidiasis is increasing worldwide. However, the epidemiology, antifungal susceptibility, and virulence of Candida spp. in most hospitals remain unclear. This study aimed to evaluate invasive candidiasis in a tertiary
Junzhu Chen +13 more
doaj +1 more source
Advanced Sustainable Systems, Volume 9, Issue 10, October 2025.Fungal mycelium‐based materials are an upcoming class of sustainable materials. Heat ‐pressing is a promising post‐processing technique to produce fungal mycelium‐based particle boards or leather substitutes. However, little is known about the mechanism involved.
Huaiyou Chen +9 more
wiley +1 more source
The seizure of illicit assets: patterns of civil forfeiture in Canada and Ireland [PDF]
, 2013 No description ...
Gallant, M Michelle, King, Colin
core +1 more source
Journal of Antimicrobial Chemotherapy, 2018 A strain of the opportunistic pathogenic yeast Candida lusitaniae was genetically engineered for full-length replacement of the FKS1 gene encoding the target of echinocandin antifungals in order to assess the impact of FKS mutations on echinocandin resistance and reduced echinocandin susceptibility (RES).FKS1 allelic exchange was achieved by ...
Isabelle Accoceberry +4 more
openaire +2 more sources
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
Advanced Science, Volume 12, Issue 37, October 6, 2025.The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda +12 more
wiley +1 more source