Results 51 to 60 of about 3,923 (195)
New cell wall-affecting antifungal antibiotics [PDF]
Capítulo 9.Fungi have emerged worldwide as increasingly frequent causes of healthcare-associated infections. Invasive fungal infections can be life-threatening.
Cortés, Juan Carlos G. +2 more
core +2 more sources
Double-Pole Approximation in Time-Dependent Density Functional Theory [PDF]
A simple approximate solution to the linear response equations of time-dependent density functional theory (TDDFT) is given. This extends the single-pole approximation (SPA) to two strongly-coupled poles. The analysis provides both an illustration of how
Appel +18 more
core +1 more source
Portrait of matrix gene expression in Candida glabrata biofilms with stress induced by different drugs [PDF]
(1) Background: Candida glabrata is one of the most significant Candida species associated with severe cases of candidiasis. Biofilm formation is an important feature, closely associated with antifungal resistance, involving alterations of gene ...
Henriques, Mariana, Rodrigues, Célia F.
core +2 more sources
Low Prevalence of fks1 Hot Spot 1 Mutations in a Worldwide Collection of Candida Strains [PDF]
ABSTRACT We evaluated the prevalence of fks1 hot spot (HS) 1 mutations among 133 Candida strains from six species displaying various caspofungin MIC values (from ≤0.008 to >8 μg/ml). Only 4 (2.9%) strains displayed FKS1 HS1 amino acid substitutions: 1 C. albicans
Mariana, Castanheira +5 more
openaire +2 more sources
New strategic insights into managing fungal biofilms [PDF]
Fungal infections have dramatically increased in the last decades in parallel with an increase of populations with impaired immunity, resulting from medical conditions such as cancer, transplantation or other chronic diseases.
Borghi, Elisa +6 more
core +4 more sources
The opportunistic fungus Candida albicans is the leading cause of invasive candidiasis in immune-compromised individuals. Drugs from the echinocandin (ECN) class, including caspofungin, are used as a first line of therapy against invasive candidiasis ...
Anshuman Yadav +3 more
doaj +1 more source
ABSTRACT Background The incidence of Candida tropicalis isolation is increasing in hospital settings. High azole resistance and mortality rates make it a pathogen that requires further analysis. Methods Fourteen azole resistant Candida glabrata clinical isolates were collected from a Lebanese hospital and analysed through whole genome sequencing for ...
Christy Chedraoui +9 more
wiley +1 more source
Combined antifungal resistance and biofilm tolerance: the global threat of Candida auris [PDF]
The enigmatic yeast Candida auris has emerged over the last decade and rapidly penetrated our consciousness. The global threat from this multidrug-resistant yeast has generated a call to arms from within the medical mycology community.
Kean, Ryan, Ramage, Gordon
core +2 more sources
Introduction/objectivesAn increase in antifungal resistant Candida strains has been reported in recent years. The aim of this study was to detect mutations in resistance genes of azole-resistant, echinocandin-resistant or multi-resistant strains using ...
Kathrin Spettel +9 more
doaj +1 more source
Molecular Epidemiology of Candida Auris Outbreak in a Major Secondary-Care Hospital in Kuwait
The emerging, often multidrug-resistant Candida auris is increasingly being associated with outbreaks in healthcare facilities. Here we describe the molecular epidemiology of a C.
Wadha Alfouzan +11 more
doaj +1 more source

