Results 61 to 70 of about 2,823 (143)

Biocide Response of Candida auris

Mycoses, Volume 69, Issue 3, March 2026.
ABSTRACT Candida auris is an emerging multidrug‐resistant yeast demonstrating remarkable persistence in healthcare environments, contributing to nosocomial transmission and outbreak persistence. Increasing disinfectant failure reports have raised concerns regarding infection control policies, as environmental reservoirs play central roles in its spread.
Sidre Erganis, Ali Ozturk, Elif Ayca Sahin, Ayse Kalkanci   +3 more
wiley   +1 more source

Emergence of Candida (Candidozyma) auris in Minas Gerais, Brazil: Genomic Surveillance to Guide Rapid Public Health Responses

Mycoses, Volume 69, Issue 2, February 2026.
ABSTRACT Background Candida (Candidozyma) auris is an emerging yeast that poses a significant global health threat due to its multidrug resistance and ability to cause healthcare‐associated outbreaks. Genomic surveillance is essential for monitoring spread, transmission and antifungal resistance.
Luiz Marcelo Ribeiro Tomé, Dhian Renato Almeida Camargo, Rafael Wesley Bastos, Sara Cândida Ferreira dos Santos, Natália Rocha Guimarães, Sílvia Helena Sousa Pietra Pedroso, Paulo Eduardo de Souza da Silva, Aristóteles Góes‐Neto, Lida Jouca de Assis Figueredo, Gabriella da Côrte Castro, Ana Maria Ribeiro Nunes Rodrigues, Flavia Ribeiro Soares Cruzeiro, Nádia Aparecida Campos Dutra, Josiane Barbosa Piedade Moura, Glauco de Carvalho Pereira, Carmem Dolores Faria, Marta Giovanetti, Felipe Campos de Melo Iani, Luiz Carlos Júnior Alcantara, Talita Émile Ribeiro Adelino   +19 more
wiley   +1 more source

Characterization of the chitin biosynthesis process as a compensatory mechanism in the fks1 mutant of Saccharomyces cerevisiae [PDF]

, 2000
Deletion of the 1,3-β-D-glucan synthase gene FKS1 in Saccharomyces cerevisiae induces a compensatory mechanism that is reflected in a significant increase in chitin synthase III (CSIII) activity, leading to high rates of chitin synthesis. Deregulation of
Castro, C, Roncero, C, J.A Trilla, Trilla, J.A, L.J Garcı́a-Rodriguez, M.H Valdivieso, Valdivieso, M.H, C Roncero, Garcı́a-Rodriguez, L.J, Durán, A, A Durán, C Castro   +11 more
core   +1 more source

Monitoring the Diversity and Antifungal Susceptibility of Candida Isolates at Adam Malik Hospital, Medan, Indonesia

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Candida species are well‐known for their capacity to cause a broad range of infections in humans. Invasive and device‐related infections caused by Candida albicans and non‐albicans contribute to a relatively high mortality rate, thereby becoming a major public health concern around the world.
Evita Mayasari, Cherry Siregar, Iftikhar Ahmed   +2 more
wiley   +1 more source

First Report of Human Infection Caused by Aspergillus steynii and Analysis of Its Whole‐Genome Characteristics

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The incidence of infections caused by rare pathogens has increased in recent years. This necessitates the development of effective diagnostic and therapeutic approaches. In this study, we report the first documented case of Aspergillus steynii‐induced pulmonary infection in humans.
Ruixuan Wang, Jingjing Chen, Na Wu, Min Yang, Ruiying Quan, Nan Xia, Hailong Li, Hua Nian, Ning Jiang, Yunzhuo Chu, Shitong Cheng, Sufei Tian, Nan-hua Chen   +12 more
wiley   +1 more source

Acquired echinocandin resistance in a Candida krusei blood isolate confirmed by mutations in the fks1 gene

, 2014
We describe a case of bloodstream infection caused by a Candida krusei strain that developed echinocandin resistance during caspofungin therapy. Three mutations were found in the HS1 region of the fks1 gene, two of them have never been reported either in
A.M. Tortorano, M.C. Esposto, L. Pitzurra, A.C.M. Prigitano, C. Santamaria, M. Cogliati   +5 more
core   +2 more sources

Yeast species-specific, differential inhibition of β-1,3-glucan synthesis by poacic acid and caspofungin

The Cell Surface, 2018
The rise of widespread antifungal resistance fuels the need to explore new classes of inhibitory molecules as potential novel inhibitors. Recently a plant natural product poacic acid (PA) was shown to inhibit β-1,3-glucan synthesis, and to have ...
Keunsook K. Lee, Karen Kubo, Jehan Abdelmoneim Abdelaziz, Iain Cunningham, Alessandra de Silva Dantas, Xiaolin Chen, Hiroki Okada, Yoshikazu Ohya, Neil A.R. Gow   +8 more
doaj   +1 more source

Structural, Mechanical, and Genetic Insights into Heat‐Pressed Fomes Fomentarius Mycelium from Solid‐State and Liquid Cultivations

Advanced Sustainable Systems, Volume 9, Issue 10, October 2025.
Fungal mycelium‐based materials are an upcoming class of sustainable materials. Heat ‐pressing is a promising post‐processing technique to produce fungal mycelium‐based particle boards or leather substitutes. However, little is known about the mechanism involved.
Huaiyou Chen, Sophie Klemm, Ernesto Scoppola, Bertram Schmidt, Yunpeng Wu, Claudia Fleck, Aleksander Gurlo, Vera Meyer, Carsten Freidank‐Pohl, Ulla Simon   +9 more
wiley   +1 more source

Stress-Induced Changes in the Lipid Microenvironment of β-(1,3)-d-Glucan Synthase Cause Clinically Important Echinocandin Resistance in Aspergillus fumigatus

mBio, 2019
Aspergillus fumigatus is a leading cause of invasive fungal infections. Resistance to first-line triazole antifungals has led to therapy with echinocandin drugs. Recently, we identified several high-minimum-effective-concentration (MEC) A.
Shruthi Satish, Cristina Jiménez-Ortigosa, Yanan Zhao, Min Hee Lee, Enriko Dolgov, Thomas Krüger, Steven Park, David W. Denning, Olaf Kniemeyer, Axel A. Brakhage, David S. Perlin   +10 more
doaj   +1 more source

Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi

Advanced Science, Volume 12, Issue 37, October 6, 2025.
The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda, Kaila Petronila Medina‐Alarcón, João Paulo Soler Gonçalves Pereira, Thais Cristina dos Anjos Sevilhano, Brigitte Aguilar‐Morón, Fernando Díaz‐Cárdenas, Lucas Silva da Cruz, Francisco Humberto Xavier‐Júnior, Eduardo Festozo Vicente, João Perdigão, Beatriz G. de la Torre, Fernando Albericio, Fernando Rogério Pavan   +12 more
wiley   +1 more source