Results 61 to 70 of about 2,691 (173)

Analysis of antifungal resistance genes in Candida albicans and Candida glabrata using next generation sequencing.

PLoS ONE, 2019
Introduction/objectivesAn increase in antifungal resistant Candida strains has been reported in recent years. The aim of this study was to detect mutations in resistance genes of azole-resistant, echinocandin-resistant or multi-resistant strains using ...
Kathrin Spettel, Wolfgang Barousch, Athanasios Makristathis, Iris Zeller, Marion Nehr, Brigitte Selitsch, Michaela Lackner, Peter-Michael Rath, Joerg Steinmann, Birgit Willinger   +9 more
doaj   +1 more source

Antifungal Potential of Cumin Spice Seeds, Cuminum cyminum, Against Aspergillus fumigatus: Mechanistic Insights Into Ergosterol, Melanin, and Biofilm Inhibition

Food Frontiers, Volume 7, Issue 4, July 2026.
Antifungal effects and underlying mechanism of the action of the supercritical fluid extracted from the cumin (Cuminum cyminum) seeds and its volatile phyto‐constituents against pathogenic Aspergillus fumigatus. ABSTRACT Spices are aromatic culinary ingredients used worldwide for enhancing food flavors, folklore therapy, and their antiseptic ...
Acharya Balkrishna, Lovely Gupta, Rani Singh, Yash Varshney, Rishabh Dev, Pardeep Nain, Savita Lochab, Anurag Varshney   +7 more
wiley   +1 more source

Reduced Candida glabrata Susceptibility Secondary to an FKS1 Mutation Developed during Candidemia Treatment [PDF]

Antimicrobial Agents and Chemotherapy, 2008
ABSTRACT We describe a case of recurring Candida glabrata infection in a 68-year-old African-American female on caspofungin therapy. The initial isolate was susceptible, but isolates recovered during following relapses were not.
John D, Cleary, Guillermo, Garcia-Effron, Stanley W, Chapman, David S, Perlin   +3 more
openaire   +2 more sources

WC1/WC2–Sre1 Transcriptional Cascade Controls Predation and Chlamydospore Formation in the Nematode‐Trapping Fungus Arthrobotrys flagrans

Microbial Biotechnology, Volume 19, Issue 7, July 2026.
Systematic functional characterization of all eight GATA‐type transcription factors in the nematode‐trapping fungus Arthrobotrys flagrans reveals a novel, light‐independent WC1/WC2–Sre1 transcriptional cascade that orchestrates both trap formation and chlamydospore development, providing actionable targets for engineering superior biocontrol strains ...
Yu Zhang, Jiafang Zuo, Qianfei Shi, Peiji Zhao, Hanbo Zhang, Minghe Mo, Guohong Li   +6 more
wiley   +1 more source

Resistance to Echinocandins Complicates a Case of Candida albicans Bloodstream Infection: A Case Report

Journal of Fungi, 2021
Invasive candidiasis is known to be one of the most common healthcare-associated complications and is caused by several Candida species. First-line drugs, particularly echinocandins, are effective, but there are increasing reports of resistance to these ...
Laura Trovato, Dafne Bongiorno, Maddalena Calvo, Giuseppe Migliorisi, Albino Boraccino, Nicolò Musso, Salvatore Oliveri, Stefania Stefani, Guido Scalia   +8 more
doaj   +1 more source

Role for Fks1 in the Intrinsic Echinocandin Resistance of Fusarium solani as Evidenced by Hybrid Expression in Saccharomyces cerevisiae [PDF]

Antimicrobial Agents and Chemotherapy, 2009
ABSTRACT The opportunistic mold Fusarium solani is intrinsically resistant to cell wall synthesis-inhibiting echinocandins (ECs), including caspofungin and micafungin. Mutations that confer acquired EC resistance in Saccharomyces cerevisiae and other normally susceptible yeast ...
Santosh K, Katiyar, Thomas D, Edlind
openaire   +2 more sources

Intracellular trafficking and localization of the β-(1,3)-glucan synthase, Fks1, are impaired in the mar1Δ mutant. [PDF]

, 2018
(A) Uptake of the lipophilic dye, FM4-64, is irregular in mar1Δ cells. Cells were incubated overnight in YPD (30°C) or TC (37°) and stained with FM4-64 for 30 minutes with shaking, followed by pelleting and refreshing in the indicated media for an ...
Carol Munro (108688), Connie B. Nichols (252902), Floyd L. Wormley Jr. (220899), Kyla S. Ost (720285), Althea Campuzano (3687070), Maria A. Kohlbrenner (5334965), Kaila M. Pianalto (5334962), Calla L. Telzrow (5334959), J. Andrew Alspaugh (252904), Shannon K. Esher (720288)   +9 more
core   +1 more source

Molecular Epidemiology of Candida Auris Outbreak in a Major Secondary-Care Hospital in Kuwait

Journal of Fungi, 2020
The emerging, often multidrug-resistant Candida auris is increasingly being associated with outbreaks in healthcare facilities. Here we describe the molecular epidemiology of a C.
Wadha Alfouzan, Suhail Ahmad, Rita Dhar, Mohammad Asadzadeh, Noura Almerdasi, Naglaa M. Abdo, Leena Joseph, Theun de Groot, Walid Q. Alali, Ziauddin Khan, Jacques F. Meis, Mohammad R. Al-Rashidi   +11 more
doaj   +1 more source

A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009-17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance [PDF]

, 2018
Item does not contain fulltextBackground: Candida auris has emerged globally as an MDR nosocomial pathogen in ICU patients. Objectives: We studied the antifungal susceptibility of C.
Shalini Upadhyay, Bansidhar Tarai, Priyanka Yadav, Kumar, A., Cheshta Sharma, Sarma, Smita, Chowdhary, Anuradha, Sharma, Cheshta, Kordalewska, Milena, Smita Sarma, Khillan, Vikas, Singh, A., Meis, Jacques F, Singh, Ashutosh, Prakash, A., Upadhyay, Shalini, Sachdeva, N., Meis, J.F.G.M., Gargi Upadhyaya, Vikas Khillan, Singh, Pradeep K, Anil Kumar, Sharma, C., Perlin, D.S., Jacques F Meis, Perlin, David S, Tarai, B., Anupam Prakash, Tarai, Bansidhar, Chowdhary, A., David S Perlin, Singh, P.K., Kordalewska, M., Yadav, P., Upadhyaya, Gargi, Anuradha Chowdhary, Prakash, Anupam, Sarma, S., Sachdeva, Neelam, Khillan, V., Ashutosh Singh, Pradeep K Singh, Yadav, Priyanka, Milena Kordalewska, Neelam Sachdeva, Upadhyaya, G., Kumar, Anil, Upadhyay, S.   +47 more
core   +1 more source

Successful Management of Candida auris Bloodstream Infection in an Elderly Patient: A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Candida auris is an emerging multidrug‐resistant pathogen frequently misidentified by conventional methods, posing diagnostic and infection‐control challenges, particularly in low‐ and middle‐income countries. We report a 74‐year‐old male in Dhaka, Bangladesh, with multiple comorbidities who developed Candidemia.
Arif Hasan Chowdhury, Tania Rahman, Nazrul Islam, Tuhin Sadique, Asif Reza Khan, Debashis Sen, Ahmed Abdullah, Dinesh Mondal, Dilruba Ahmed   +8 more
wiley   +1 more source