Results 111 to 120 of about 2,691 (173)

Paracoccidioides spp.: the structural characterization of extracellular matrix, expression of glucan synthesis and associated genes and adhesins during biofilm formation

Frontiers in Microbiology
The genus Paracoccidioides includes Paracoccidioides lutzii and the Paracoccidioides brasiliensis complex, which comprises four phylogenetic species. A key feature distinguishing planktonic growth from biofilm is the presence of a 3D extracellular matrix
Lariane Teodoro Oliveira, Caroline Maria Marcos, Ana Karla Lima Freire Cabral, Ana Karla Lima Freire Cabral, Kaila Petronila Medina-Alarcón, Regina Helena Pires, Ana Marisa Fusco-Almeida, Maria José Soares Mendes-Giannini   +7 more
doaj   +1 more source

La ruta de la proteina Quinasa C en Saccharomyces cerevisiae. Conexiones con el control del ciclo celular. [PDF]

, 2005
RESUMEN La ruta de la Proteína quinasa C en Saccharomyces cerevisiae desempeña funciones esenciales en el control de la integridad celular y además se ha sugerido que participa en la coordinación entre el crecimiento y la división celular.
Martínez Bono, Bárbara
core  

A pan-azole and pan-echinocandin resistant Wickerhamomyces anomalus isolate causing bloodstream infection: ERG11Y140F, K151R with copy number variation and FKS1 F665S mutation

International Journal of Medical Microbiology
Fungal infections pose a growing global threat, particularly due to the emergence of multidrug-resistant pathogens. This study reports the first globally documented case of a Wickerhamomyces anomalus isolate (XN272) displaying dual high-level resistance ...
Zhengyu Luo, Yating Ning, Rongchen Dai, Ailifeire Ainiwaer, Yanhong Li, Ruike Zhang, Meng Xiao, Xiaoxi Wang, Yang Yang, Yuyan Huang, Dingding Li, Lingli Liu, Roujie Huang, Tingying Xu, Yingchun Xu, Zhiyong Liu, Li Zhang, Tianshu Sun   +17 more
doaj   +1 more source

Emergence of Echinocandin Resistance due to a Point Mutation in the fks1 Gene in a Patient with Chronic Pulmonary Aspergillosis

Antimicrobial Agents and Chemotherapy, 2017
We have identified the first case of fks1 hot spot 1 point mutation causing echinocandin resistance in a clinical Aspergillus fumigatus isolate recovered from a patient with an aspergilloma and chronic pulmonary aspergillosis who first failed azole therapy and then was treated with micafungin.
Jiménez-Ortigosa, Cristina, Moore, Caroline, Denning, David; id_orcid 0000-0001-5626-2251, Perlin, David S.   +3 more
openaire   +1 more source

Structural basis of fungal β-1,3-glucan synthase inhibition by caspofungin. [PDF]

Nature
Ren Z, Chhetri A, Liu C, Offner S, Sharma K, Borgnia MJ, Im W, Yokoyama K, Lee SY.   +8 more
europepmc   +1 more source

Mutational landscape and molecular bases of echinocandin resistance in Saccharomyces cerevisiae. [PDF]

Genetics
Durand R, Torbey AG, Giguere M, Pageau A, Dubé AK, Lagüe P, Landry CR.   +6 more
europepmc   +1 more source

Multidimensional assessment of in-host fitness costs of echinocandin resistance in the opportunistic fungal pathogen <i>Candida glabrata</i> reveals the niche-specific requirement for <i>FKS1</i> and <i>FKS2</i> during infection and gut colonization. [PDF]

Antimicrob Agents Chemother
Arastehfar A, Daneshnia F, Hovhannisyan H, Cabrera N, Jusuf S, Salehi M, Mansour MK, Gabaldón T, Shor E, Perlin DS.   +9 more
europepmc   +1 more source

Molecular and Phenotypic Characterization of Multidrug-Resistant <i>Aspergillus fumigatus</i> Clinical Isolates in Republic of Korea. [PDF]

J Fungi (Basel)
Lee YH, An Y, Lee YJ, Lee J, Kim SY, Kang BH.   +5 more
europepmc   +1 more source

Echinocandin Resistance in Candida auris Occurs in the Murine Gastrointestinal Tract Due to FKS1 Mutations

Echinocandin Resistance in Candida auris Occurs in the Murine Gastrointestinal Tract Due to FKS1 Mutations
Candida auris is resistant to multiple antifungal agents. This study investigated its antifungal susceptibility and explored FKS1 mutations across the isolates from mice enterically colonized with wild-type C. auris and treated with echinocandin. Resistant C. auris with FKS1 mutations, including S639F, S639Y, D642Y, R1354H, or R1354Y, were isolated and
openaire   +1 more source

Updated Genomic Epidemiologic Description of Candida (Candidozyma) auris, United States. [PDF]

Emerg Infect Dis
Parnell LA, Dos Santos AR, Forsberg K, Lyman M, Misas E, Gade L, Sexton DJ, Litvintseva AP, Chow NA.   +8 more
europepmc   +1 more source