A Calcineurin Inhibitor as an Enhancer of <i>Candida</i> Susceptibility to Anidulafungin. [PDF]
ACS OmegaRovira I +7 more
europepmc +1 more source
Echinocandin Resistance in Candida auris Occurs in the Murine Gastrointestinal Tract Due to FKS1 MutationsCandida auris is resistant to multiple antifungal agents. This study investigated its antifungal susceptibility and explored FKS1 mutations across the isolates from mice enterically colonized with wild-type C. auris and treated with echinocandin. Resistant C. auris with FKS1 mutations, including S639F, S639Y, D642Y, R1354H, or R1354Y, were isolated and
openaire +1 more source
Deciphering the multidrug resistance paradigm in <i>Candida auris</i>. [PDF]
Antimicrob Agents ChemotherSantana DJ +3 more
europepmc +1 more source
Antifungal efficacy of linoleic-acid-rich Cucurbita pepo L. seed oil revealed by GC-MS profiling of lipids and bioactive markers, ergosterol depletion, and network pharmacology. [PDF]
BMC MicrobiolMohamed ET.
europepmc +1 more source
SCY-247, a novel second-generation triterpenoid antifungal, demonstrates high in vitro activity against genetically diverse Candida auris isolates, including FKS1 mutants. [PDF]
J Antimicrob ChemotherSpruijtenburg B, de Groot T, Meijer EFJ.
europepmc +1 more source
A Candidozyma (Candida) auris-Optimized Episomal Plasmid-Induced Cas9-Editing System Reveals the Direct Impact of the S639F-Encoding FKS1 Mutation. [PDF]
J Infect DisDoorley LA +3 more
europepmc +1 more source
Experimental Evolution of Pathogenic <i>Candida</i> spp.: Insights into Adaptive Processes and Evolutionary Dynamics. [PDF]
MicroorganismsSousa G, Correia I, Bezerra AR.
europepmc +1 more source
The Upcoming Antifungal Drugs in Clinical Development for the Treatment of Invasive Candidiasis. [PDF]
Infect Drug ResistZubovskaia A, Vazquez JA.
europepmc +1 more source
Genomic epidemiology of Colombian resistant <i>Candida auris</i> isolates. [PDF]
Antimicrob Agents ChemotherAlvarado Casas ML +4 more
europepmc +1 more source