Results 131 to 140 of about 2,823 (143)

Impact of FKS1 Genotype on Echinocandin In Vitro Susceptibility in Candida auris and In Vivo Response in a Murine Model of Infection

Antimicrobial Agents and Chemotherapy, 2022
Anup Ghosh, Shamanth A Shankarnarayan, Harsimran Kaur   +2 more
exaly  

Structural and mechanistic insights into fungal β-1,3-glucan synthase FKS1

Nature, 2023
Liu Xiaotian, Zhang Mingjie, Hongjun Yu   +2 more
exaly  

Fatal Breakthrough Candidemia in an Immunocompromised Patient in Kuwait Due to Candida auris Exhibiting Reduced Susceptibility to Echinocandins and Carrying a Novel Mutation in Hotspot-1 of FKS1

Journal of Fungi (Basel, Switzerland), 2022
Mohammad Asadzadeh, Alfouzan W, Khaled Alobaid   +2 more
exaly  

Do Candida albicans Isolates with Borderline Resistant Micafungin MICs Always Harbor FKS1 Hot Spot Mutations?

Journal of Fungi (Basel, Switzerland), 2021
Birgit Willinger, Kathrin Spettel, Iris Camp   +2 more
exaly  

Novel Non-Hot Spot Modification in Fks1 of Candida auris Confers Echinocandin Resistance

Antimicrobial Agents and Chemotherapy, 2023
Milena Kordalewska, João Nóbrega de Almeida Junior, David Perlin   +2 more
exaly  

Molecular characterisation of Candida auris isolates from immunocompromised patients in a tertiary‐care hospital in Kuwait reveals a novel mutation in FKS1 conferring reduced susceptibility to echinocandins

Mycoses, 2022
Theun de Groot, Mohammad Asadzadeh, Meis Jf   +2 more
exaly  

Up-regulation of genes encoding glycosylphosphatidylinositol (GPI)-attached proteins in response to cell wall damage caused by disruption of FKS1 in Saccharomyces cerevisiae

Molecular Genetics and Genomics, 2000
M Arisawa
exaly  

Emergence of Echinocandin Resistance Due to a Point Mutation in the fks1 Gene of Aspergillus fumigatus in a Patient with Chronic Pulmonary Aspergillosis

Antimicrobial Agents and Chemotherapy, 2017
David Denning, David Perlin, Cristina Jimenez-Ortigosa   +2 more
exaly  

The Paradoxical Effect of Echinocandins in Aspergillus fumigatus Relies on Recovery of the β-1,3-Glucan Synthase Fks1

Antimicrobial Agents and Chemotherapy, 2017
Johannes Wagener
exaly  

Targeting Fks1 proteins for novel antifungal drug discovery

Trends in Pharmacological Sciences
Vinit Kumar, Ge-Fei Hao
exaly