Results 121 to 130 of about 2,823 (143)

Resistance gene mutations and phylogenetic relationships in <i>Candidozyma auris</i> isolates from Russia. [PDF]

Front Cell Infect Microbiol
Oganesyan EG, Zhuk AS, Gusarova KV, Kovyrshin SV, Alekseevskaya ES, Orlova OE, Khostelidi SN, Kozlova OP, Liubimova AV, Taraskina AE, Vasilyeva NV.   +10 more
europepmc   +1 more source

A quiet but growing threat: Global perspectives on antifungal resistance and future therapeutic approaches. [PDF]

Indian J Pharmacol
Gurajala S, Challapilla M.
europepmc   +1 more source

Clinical and Molecular Epidemiological Characteristics of 26 Bloodstream Infection Cases Caused by Candida tropicalis. [PDF]

Mycopathologia
Lin W, Yang Q, Lin Z, Liu S, Zhang L, Jiang Y, Fang J, Peng Y, Guo P.   +8 more
europepmc   +1 more source

Pan-Echinocandin Resistant C. parapsilosis Harboring an F652S Fks1 Alteration in a Patient with Prolonged Echinocandin Therapy

Journal of Fungi (Basel, Switzerland), 2022
The isolation of a pan-echinocandin-resistant Candida parapsilosis strain (anidulafungin, caspofungin, micafungin and rezafungin EUCAST MICs > 8 mg/L) from urine of a patient following prolonged exposure to echinocandins (38 days of micafungin ...
Anastasia Spiliopoulou, Maiken Cavling Arendrup, Maria Siopi   +2 more
exaly   +1 more source

Echinocandin Resistance in Candida auris Occurs in the Murine Gastrointestinal Tract Due to FKS1 Mutations [PDF]

Antimicrobial Agents and Chemotherapy, 2023
Candida auris is resistant to multiple antifungal agents. This study investigated its antifungal susceptibility and explored FKS1 mutations across the isolates from mice enterically colonized with wild-type C.
Takahiro Takazono, Koichi Makimura, Tatsuro Hirayama   +2 more
exaly   +2 more sources

Fitness and Virulence Costs of Candida albicans FKS1 Hot Spot Mutations Associated With Echinocandin Resistance [PDF]

Journal of Infectious Diseases, 2011
The identification of FKS1 mutations in Candida albicans associated with echinocandin resistance has raised concerns over the spread of drug-resistant strains. We studied the impact of fks1 mutations on C. albicans virulence and fitness.
Konstantinos Leventakos, Russell Lewis
exaly   +2 more sources

Evaluation of a Novel FKS1 R1354H Mutation Associated with Caspofungin Resistance in Candida auris Using the CRISPR-Cas9 System [PDF]

Journal of Fungi (Basel, Switzerland), 2023
Nagasaki University (長崎大学)博士(医学)Outbreaks of invasive infections, with high mortality rates, caused by multidrug-resistant Candida auris have been reported worldwide. Although hotspot mutations in FKS1 are an established cause of echinocandin resistance,
Naoki Iwanaga, Takahiro Takazono, Nana Nakada-Motokawa   +2 more
exaly   +1 more source