Results 141 to 150 of about 2,691 (173)

Puf4 is methylated and exhibits a temperature-dependent interactome in <i>Cryptococcus neoformans</i>. [PDF]

Microbiol Spectr
Kalem MC, Duffy S, Bloom ALM, Shen S, Kaur JN, Qu J, Panepinto JC.   +6 more
europepmc   +1 more source

Effective treatment of systemic candidiasis by synergistic targeting of cell wall synthesis. [PDF]

Nat Commun
Chung JY, Hong YK, Jeon E, Yang S, Park A, Weissleder R, Chong YP, Chung HJ.   +7 more
europepmc   +1 more source

Evaluation of the MIC test strips for antifungal susceptibility testing of <i>Candidozyma auris</i> (<i>Candida auris</i>) using a representative international collection of isolates. [PDF]

J Clin Microbiol
Siopi M, Leventaki S, Pachoulis I, Spruijtenburg B, Meis JF, Pournaras S, Vrioni G, Tsakris A, Meletiadis J.   +8 more
europepmc   +1 more source

Genomic Dynamics of the Emergent <i>Candida auris</i>: Exploring Climate-dependent Trends. [PDF]

Open Forum Infect Dis
Jara M, Frias-De-Diego A, Petit RA, Wang Y, Frias M, Lanzas C.   +5 more
europepmc   +1 more source

Phylogenomic analysis and genetic mechanisms of antifungal resistance in clinical isolates of <i>Candida glabrata</i> (<i>Nakaseomyces glabratus</i>) from across Canada, 2013-2020. [PDF]

Microbiol Spectr
De Luca DG, Alexander DC, Dingle TC, Dufresne PJ, Fuller J, German GJ, Haldane D, Hoang LM, Jiao L, Kus JV, Li L, Malejczyk K, Sheitoyan-Pesant C, Stein M, Graham M, Van Domselaar G, Bharat A.   +16 more
europepmc   +1 more source

Correction for Corrales et al., "Characterization of a selective, iron-chelating antifungal compound that disrupts fungal metabolism and synergizes with fluconazole". [PDF]

Microbiol Spectr
Corrales J, Ramos-Alonso L, González-Sabín J, Ríos-Lombardía N, Trevijano-Contador N, Engen Berg H, Skottvoll FS, Moris F, Zaragoza O, Chymkowitch P, Garcia I, Enserink JM.   +11 more
europepmc   +1 more source

Fitness and Virulence Costs of Candida albicans FKS1 Hot Spot Mutations Associated With Echinocandin Resistance [PDF]

Journal of Infectious Diseases, 2011
The identification of FKS1 mutations in Candida albicans associated with echinocandin resistance has raised concerns over the spread of drug-resistant strains. We studied the impact of fks1 mutations on C. albicans virulence and fitness. Compared with wild-type strains for FKS1, echinocandin-resistant C.
Konstantinos Leventakos, Russell Lewis
exaly   +8 more sources

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Structural and mechanistic insights into fungal β-1,3-glucan synthase FKS1

Nature, 2023
The membrane-integrated synthase FKS is involved in the biosynthesis of β-1,3-glucan, the core component of the fungal cell wall1,2. FKS is the target of widely prescribed antifungal drugs, including echinocandin and ibrexafungerp3,4. Unfortunately, the mechanism of action of FKS remains enigmatic and this has hampered development of more effective ...
Liu Xiaotian, Yanan Wu, Zhang Mingjie
exaly   +3 more sources