Results 81 to 90 of about 4,417 (197)
The first invasive Candida auris infection in Taiwan
Emerging Microbes and Infections, 2022 Candida auris, a multidrug resistant pathogenic yeast, has spread worldwide and caused several outbreaks in healthcare settings. Here, we report the first case of C.
Yu-Te Tsai +7 more
doaj +1 more source
On the influence of cell size in physically-based distributed hydrological modelling to assess extreme values in water resource planning [PDF]
, 2012 This paper studies the influence of changing spatial resolution on the implementation of distributed hydrological modelling for water resource planning in Mediterranean areas.
A. Millares +4 more
core +1 more source
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
Advanced Science, Volume 12, Issue 37, October 6, 2025.The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda +12 more
wiley +1 more source
A Glucan Synthase FKS1 Homolog in Cryptococcus neoformans Is Single Copy and Encodes an Essential Function [PDF]
Journal of Bacteriology, 1999 ABSTRACT Cryptococcal meningitis is a fungal infection, caused by Cryptococcus neoformans , which is prevalent in immunocompromised patient populations. Treatment failures of this disease are emerging in the clinic, usually associated with long-term treatment with existing antifungal agents.
J R, Thompson +9 more
openaire +2 more sources
Two echinocandin-resistant Candida glabrata FKS mutants from South Africa
Medical Mycology Case Reports, 2016 Echinocandins are recommended as first-line agents to treat invasive infections caused by Candida glabrata since this organism is inherently less susceptible to azoles. However, resistance to echinocandins has been described in C.
Serisha D. Naicker +6 more
doaj +1 more source
Journal of Fungi, 2023 Echinocandins, used for the prevention and treatment of invasive fungal infections, have led to a rise in breakthrough infections caused by resistant Candida species.
Laura N. Silva +8 more
doaj +1 more source
CWI‐MAPKs Regulate the Formation of Hyphopodia Required for Virulence in Ceratocystis fimbriata
Molecular Plant Pathology, Volume 26, Issue 7, July 2025.The Slt2‐Swi6 pathway is crucial for the pathogenicity of Ceratocystis fimbriata. It regulates septin assembly at the base of the penetration peg, thereby influencing penetration peg formation—a key virulence determinant. ABSTRACT Ceratocystis fimbriata is a destructive fungal pathogen that infects various economic crops.
Kailun Lu +6 more
wiley +1 more source
Emerging Threats in Antifungal-Resistant Fungal Pathogens. [PDF]
, 2016 The use of antifungal drugs in the therapy of fungal diseases can lead to the development of antifungal resistance. Resistance has been described for virtually all antifungal agents in diverse pathogens, including Candida and Aspergillus species.
Sanglard, D.
core +2 more sources
Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors [PDF]
Antimicrobial Agents and Chemotherapy, 1997 Pneumocandins and echinocandins are fungicidal antibiotics, currently in clinical development, that inhibit 1,3-beta-D-glucan synthase (GS) in several human fungal pathogens. We have identified a gene from the diploid organism Candida albicans that encodes a target of these inhibitors.
C M, Douglas +11 more
openaire +2 more sources
Frontiers in Cellular and Infection Microbiology, 2021 BackgroundThe incidence of invasive candidiasis is increasing worldwide. However, the epidemiology, antifungal susceptibility, and virulence of Candida spp. in most hospitals remain unclear. This study aimed to evaluate invasive candidiasis in a tertiary
Junzhu Chen +13 more
doaj +1 more source