Results 61 to 70 of about 45,388 (244)

STUDIES ON FLAVIN ADENINE DINUCLEOTIDE BIOSYNTHESIS USING P32-LABELED FLAVIN MONONUCLEOTIDE

THE JOURNAL OF VITAMINOLOGY, 1956
The amount of P32 in FMN used as a substrate and that in FAD obtained enzymatically were proved to be equal. In other words, the phosphoric acid of FMN was incorporated in toto in FAD, according to the formula previously indicated. The determination of pyrophosphoric acid was fairly difficult; Schrecker and Kornberg (6), in the biosynthesis of ...
K, HOTTA, R, KATSUNUMA, K, WATARAI, T, UCHIDA, E, ISHIKAWA, J, ITAYA, N, KATSUNUMA   +6 more
openaire   +3 more sources

Modular Engineering of the Flavin Pathway in Escherichia coli for Improved Flavin Mononucleotide and Flavin Adenine Dinucleotide Production.

Journal of Agricultural and Food Chemistry, 2019
In this work, modular engineering of Escherichia coli was peformed to improve flavin production and the conversion ratio of riboflavin (RF) to FMN/FAD.
Shuang Liu, Na Diao, Zhiwen Wang, Wenyu Lu, Ya-Jie Tang, Tao Chen   +5 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Riboflavin-Responsive and -Non-responsive Mutations in FAD Synthase Cause Multiple Acyl-CoA Dehydrogenase and Combined Respiratory-Chain Deficiency [PDF]

, 2017
open48siMultiple acyl-CoA dehydrogenase deficiencies (MADDs) are a heterogeneous group of metabolic disorders with combined respiratory-chain deficiency and a neuromuscular phenotype.

core   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

Advanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge, Zhao Guo, Zhiming Zhang, Lanlu Lu, Zesong Ruan, Tingwang Shi, Yunfeng Chen, Ju Huang, Chaoliang Tan, Han Lin   +9 more
wiley   +1 more source

A Photoswitchable HaloTag for Spatiotemporal Control of Fluorescence in Living Cells

Angewandte Chemie, Volume 137, Issue 50, December 8, 2025.
Photoswitchable fluorophores are critical for advanced bioimaging. Here, we develop a photoswitchable self‐labeling HaloTag that can reversibly modulate the emission of a bound fluorogenic dye via a light‐induced conformational change. In living cells, this tunable chemigenetic system enables precise spatiotemporal activation and control of emitter ...
Franziska Walterspiel, Begoña Ugarte‐Uribe, Jonas Weidenhausen, Merrin Vincent, Kaarjel K. Narayanasamy, Anna Dimitriadi, Arif Ul Maula Khan, Martin Fritsch, Christoph W. Müller, Timo Zimmermann, Claire Deo   +10 more
wiley   +2 more sources

Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis

Advanced Science, EarlyView.
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang, Xitong Song, Shuming Cheng, Yiwen Shen, Jie Zhang, Yaru Wang, Huiying Luo, Bin Yao, Binju Wang, Tao Tu   +9 more
wiley   +1 more source

Effects of Flavin-Goethite Interaction on Goethite Reduction by Shewanella decolorationis S12

Frontiers in Microbiology, 2019
Flavin mononucleotide (FMN) and riboflavin are structurally similar flavins, except for the presence of a phosphate group on the FMN molecule. They are used by a variety of electroactive bacteria as extracellular electron shuttles in microbial Fe ...
Gang Zhao, Gang Zhao, Enze Li, Enze Li, Jianjun Li, Jianjun Li, Fei Liu, Fei Liu, Xunan Yang, Xunan Yang, Meiying Xu, Meiying Xu   +11 more
doaj   +1 more source

Biotransformation of explosives by the old yellow enzyme family of flavoproteins [PDF]

, 2004
Several independent studies of bacterial degradation of nitrate ester explosives have demonstrated the involvement of flavin-dependent oxidoreductases related to the old yellow enzyme (OYE) of yeast. Some of these enzymes also transform the nitroaromatic
Bruce, N.C., Rathbone, D.A., Scrutton, N.S., Williams, R.E.   +3 more
core   +2 more sources

A “Hot Spring” Mimetic Aerogel Loaded with Multiple Amino Acids Modulates the Chronic Inflammatory Microenvironment Through Metabolic Reprogramming

Advanced Science, EarlyView.
The SrCuSi4O₁₀ bioceramic particles mimic the effects of hot spring therapy by increasing the local wound temperature, which enhances the absorption of amino acids and stimulates cell metabolism. The amino acid uptake supports cellular glutathione redox reactions, helping to mitigate oxidative stress.
Bo Li, Dandan Jin, Fei Li, Jianliang Shen, Jiang Chang, Chen Yang, Shixuan Chen, Yi Zhang   +7 more
wiley   +1 more source