Fluorescence lifetime imaging endoscopy [PDF]
SPIE Proceedings, 2011 We present two FLIM endoscopes for clinical imaging and in vivo cell biology. For subcellular confocal imaging we demonstrated the first confocal FLIM endomicroscope, implementing TCSPC with a Cellvizio®GI, which we have now developed as a self-contained wheeled instrument (1.0 × 0.7 m) incorporating a tunable excitation laser and acquiring images ...
Kennedy, GT +11 more
openaire +3 more sources
Hyperdimensional Imaging Contrast Using an Optical Fiber
Sensors, 2021 Fluorescence properties of a molecule can be used to study the structural and functional nature of biological processes. Physical properties, including fluorescence lifetime, emission spectrum, emission polarization, and others, help researchers probe a ...
Jenu V. Chacko +4 more
doaj +1 more source
Time-resolved FRET fluorescence spectroscopy of visible fluorescent protein pairs [PDF]
, 2010 Förster resonance energy transfer (FRET) is a powerful method for obtaining information about small-scale lengths between biomacromolecules. Visible fluorescent proteins (VFPs) are widely used as spectrally different FRET pairs, where one VFP acts as a ...
Birch, D.J.S. +6 more
core +9 more sources
Investigating photoexcitation-induced mitochondrial damage by chemotherapeutic corroles using multimode optical imaging [PDF]
, 2012 We recently reported that a targeted, brightly fluorescent gallium corrole (HerGa) is highly effective for breast tumor detection and treatment.
Farkas, Daniel L. +7 more
core +1 more source
IMAGING ARTIFACTS IN FLUORESCENCE LIFETIME IMAGING OPHTHALMOSCOPY
Retina, 2021 Purpose: To investigate and quantify the influence of imaging artifacts on retinal fluorescence lifetime (FLIO) values and to provide helpful hints and tricks to avoid imaging artifacts and to improve FLIO image acquisition quality.
Chantal Dysli +5 more
openaire +4 more sources
Aggregation-induced emission luminogen for in vivo three-photon fluorescence lifetime microscopic imaging [PDF]
Journal of Innovative Optical Health Sciences, 2019 Compared with visible light, near-infrared (NIR) light has deeper penetration in biological tissues. Three-photon fluorescence microscopy (3PFM) can effectively utilize the NIR excitation to obtain high-contrast images in the deep tissue.
Huwei Ni +5 more
doaj +1 more source
Frontiers in Oncology, 2021 Maximal safe resection is a key strategy for improving patient prognosis in the management of brain tumors. Intraoperative fluorescence guidance has emerged as a standard in the surgery of high-grade gliomas.
David Reichert +17 more
doaj +1 more source
Multimode optical imaging for translational chemotherapy: in vivo tumor detection and delineation by targeted gallium corroles [PDF]
, 2011 We report the feasibility of tumor detection and delineation in vivo using multimode optical imaging of targeted gallium corrole (HerGa). HerGa is highly effective for targeted HER2+ tumor elimination in vivo, and it emits intense fluorescence.
Farkas, Daniel L. +4 more
core +1 more source
Tapered optical fibers as tools for probing magneto-optical trap characteristics [PDF]
, 2009 We present a novel technique for measuring the characteristics of a magneto-optical trap for cold atoms by monitoring the spontaneous emission from trapped atoms coupled into the guided mode of a tapered optical nanofiber.
Chakrabarti, S. +4 more
core +2 more sources
Timing and Operating Mode Design for Time-Gated Fluorescence Lifetime Imaging Microscopy
The Scientific World Journal, 2013 Steady-state fluorence imaging and time-resolved fluorescence imaging are two important areas in fluorescence imaging research. Fluorescence lifetime imaging is an absolute measurement method which is independent of excitation laser intensity ...
Chao Liu +3 more
doaj +1 more source