Results 21 to 30 of about 150,148 (211)
Activation of Rho-kinase and focal adhesion kinase regulates the organization of stress fibers and focal adhesions in the central part of fibroblasts [PDF]
PeerJ, 2017 Specific regulation and activation of focal adhesion kinase (FAK) are thought to be important for focal adhesion formation, and activation of Rho-kinase has been suggested to play a role in determining the effects of FAK on the formation of stress fibers
Kazuo Katoh
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Bioactive Materials, 2022 Focal adhesion complexes function as the mediators of cell-extracellular matrix interactions to sense and transmit the extracellular signals. Previous studies have demonstrated that cardiomyocyte focal adhesions can be modulated by surface topographic ...
Huaiyu Shi +9 more
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Diverse cell junctions with unique molecular composition in tissues of a sponge (Porifera)
EvoDevo, 2019 The integrity and organization of animal tissues depend upon specialized protein complexes that mediate adhesion between cells with each other (cadherin-based adherens junctions), and with the extracellular matrix (integrin-based focal adhesions ...
Jennyfer M. Mitchell, Scott A. Nichols
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F1000Research, 2013 The Focal Adhesion Analysis Server (FAAS) is a web-based implementation of a set of computer vision algorithms designed to quantify the behavior of focal adhesions in cells imaged in 2D cultures.
Matthew E Berginski, Shawn M Gomez
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Cell Death and Disease, 2023 Numerous studies have investigated the various cellular responses against genotoxic stress, including those mediated by focal adhesions. We here identified a novel type of focal adhesion remodelling that occurs under genotoxic stress conditions, which ...
Masatsune Tsujioka +8 more
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Haematologica, 2018 Mantle cell lymphoma and other lymphoma subtypes often spread to the bone marrow, and stromal interactions mediated by focal adhesion kinase frequently enhance survival and drug resistance of the lymphoma cells. To study the role of focal adhesion kinase
Martina Rudelius +7 more
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PLoS ONE, 2012 The speed of cell migration on 2-dimensional (2D) surfaces is determined by the rate of assembly and disassembly of clustered integrin receptors known as focal adhesions.
Jessie Zhong +7 more
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Differential regulation of adhesion complex turnover by ROCK1 and ROCK2. [PDF]
PLoS ONE, 2012 ROCK1 and ROCK2 are serine/threonine kinases that function downstream of the small GTP-binding protein RhoA. Rho signalling via ROCK regulates a number of cellular functions including organisation of the actin cytoskeleton, cell adhesion and cell ...
Frances E Lock +4 more
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Biology Open, 2016 Several focal adhesion proteins are known to cooperate with integrins to link the extracellular matrix to the actin cytoskeleton; as a result, many intracellular signaling pathways are activated and several focal adhesion complexes are formed.
Ana L. Roa-Espitia +7 more
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Wound-induced polyploidization is dependent on Integrin-Yki signaling
Biology Open, 2021 A key step in tissue repair is to replace lost or damaged cells. This occurs via two strategies: restoring cell number through proliferation or increasing cell size through polyploidization.
Rose Besen-McNally +2 more
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