Results 241 to 250 of about 83,046 (264)

Requirement of Caveolae Microdomains in Extracellular Signal‐Regulated Kinase and Focal Adhesion Kinase Activation Induced by Endothelin‐1 in Primary Astrocytes

Journal of Neurochemistry, 1999
Abstract : Endothelin‐1 (ET‐1) mitogenic activity in astrocytes is mediated by the activation of the extracellular signal‐regulated kinase (ERK) pathway together with the Rho‐dependent activation of the focal adhesion kinase (FAK) pathway. To clarify the mechanisms responsible for the coordinate activation of both pathways in the ET‐1 signal ...
A, Teixeira, N, Chaverot, C, Schröder, A D, Strosberg, P O, Couraud, S, Cazaubon   +5 more
openaire   +2 more sources

[Expression of deleted in liver cancer 1 and phosphorelated focal adhesion kinase in breast cancer].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2013
To analyze the expression of deleted in liver cancer 1 (DLC1) and phosphorelated focal adhesion kinase (p-FAK) in breast cancer tissue to further understand the molecular mechanisms of the carcinogenesis and metastasis of breast cancer.Immunohistochemistry was employed to determine the protein level of DLC1 and p-FAK in 61 breast cancer, 30 benign ...
Yun, Feng, Hui-xing, Zhou, Jun-hong, Li, Zhen-yu, Li, Wei-gang, Cheng, Meng-lin, Jin, Liang, He   +6 more
openaire   +1 more source

Structural basis of Focal Adhesion Kinase activation on lipid membranes

EMBO Journal, 2020
Ricardo D Righetto, Christina Schoenherr, Pilar Redondo   +2 more
exaly  

Faculty Opinions recommendation of Focal adhesion kinase in netrin-1 signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2004
openaire   +2 more sources

Focal adhesion kinase—An emerging viable target in cancer and development of focal adhesion kinase inhibitors

Chemical Biology and Drug Design, 2021
Tabassum Khan
exaly  

Focal adhesion kinase inhibitors in the treatment of solid tumors: Preclinical and clinical evidence

Drug Discovery Today, 2022
Martin J Lavecchia, Ignacio E Leon
exaly  

Focal adhesion kinase and associated proteins

Current Opinion in Cell Biology, 1994
Michael D Schaller, J Thomas Parsons, J T Parsons   +2 more
exaly  

Structural and mechanistic insights into mechanoactivation of focal adhesion kinase

Proceedings of the National Academy of Sciences of the United States of America, 2019
Magnus S Bauer, Fabian Baumann, Csaba Daday   +2 more
exaly  

Focal adhesion kinase as a potential target in oncology

Expert Opinion on Pharmacotherapy, 2003
Gordon W Mclean, Egle Avizienyte, Margaret C Frame   +2 more
exaly  

Endothelin-1 Induction Of Focal Adhesion Kinase In Normal Human Lung Fibroblasts Is Dependent On Rho-kinase

B66. FIBROBLAST MATRIX, CYTOSKELETON, AND MIGRATION, 2010
Priya Kulasekaran, Victor J. Thannickal, Jeffrey C. Horowitz   +2 more
openaire   +1 more source