Results 261 to 270 of about 145,198 (308)

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review). [PDF]

Int J Mol Med
Chen XM, Liang YB, Zuo JX, Yang ZS, Zhang LY, Zhang XY, Wan P, Ke Y.   +7 more
europepmc   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

Molecular docking analysis with IC₅₀ Assay FAK against for FDA approved drugs. [PDF]

Bioinformation
Gandhi Z, D Tang D, Nayak A, D Belani J.
europepmc   +1 more source

Thrombomodulin facilitates melanoma progression via FAK- and ezrin-mediated phenotypic plasticity. [PDF]

J Biomed Sci
Kuo CH, Sie RH, Ku YC, Wu CL, Hsu CK, Lai CH, Wu HL.   +6 more
europepmc   +1 more source

OptoTAT reveals microtubule acetylation as a rapid trigger for GEF-H1-mediated cell migration. [PDF]

J Cell Biol
Deb Roy A, Gonzalez CS, Stanislauskas M, Shahid F, Yadav E, Rezek J, Inoue T.   +6 more
europepmc   +1 more source

The dual-specificity phosphatase JSP1 regulates neutrophil adhesion via integrin-SRC signaling in vascular inflammation. [PDF]

J Biol Chem
Li L, Tonks NK.
europepmc   +1 more source

Topographical design principles for osteochondral tissue engineering. [PDF]

Bioact Mater
Aboal-Castro L, Kolliopoulos VK, Alvarez-Lorenzo C, Mikos AG, Diaz-Gomez L.   +4 more
europepmc   +1 more source

Beyond miRNA Cargo Profiles: Anti-Inflammatory Roles of Extracellular Vesicle-Enriched miRNAs Derived From Human Intervertebral Disc Cells Unveiled by Functional Testing. [PDF]

J Extracell Biol
Li L, Sun A, Ghazizadeh S, Al-Jallad H, Upshaw K, Alfaisali S, Ouellet J, Jarzem P, Cherif H, Haglund L.   +9 more
europepmc   +1 more source