Results 31 to 40 of about 386,087 (253)
Vinculin expression in MC3T3-E1 cells in response to mechanical stimulus
Data in Brief, 2016 Loading frequency is known to influence the expression of the focal adhesions of the adherent cells. A small cyclical tensile force was transmitted to mouse pre-osteoblast MC3T3-E1 cells through PDMS substrates of varying stiffness.
J.J. Cora-Cruz +2 more
doaj +1 more source
The inner lives of focal adhesions
, 2002 In focal adhesions of eukaryotic cells, transmembrane receptors of the integrin family and a large set of adaptor proteins form the physical link between the extracellular substrate and the actin cytoskeleton.
Wehrle-Haller, Bernhard, Imhof, Beat
core +3 more sources
PLoS ONE, 2012 A minimal model of cellular mechanosensing system that consists of a single stress fiber adhering on a substrate via two focal adhesions made of catch bonds is adopted to investigate the phenomena of cell reorientation on substrates induced by an applied
Bin Chen +4 more
doaj +1 more source
mBio, 2021 Campylobacter jejuni is a major foodborne pathogen that exploits the focal adhesions of intestinal cells to promote invasion and cause severe gastritis.
Courtney M. Klappenbach +4 more
doaj +1 more source
CrkL directs ASAP1 to peripheral focal adhesions [PDF]
, 2003 Searching for proteins in platelets that can interact with the N-terminal SH3 domain of CrkL (using a combination of a pull-down assay followed by mass spectrometry), we have found that human platelets express an ADP-ribosylation factor (Arf)-specific ...
Shinya Tanaka +31 more
core +1 more source
, 2016 Cell Example: a) vinculin staining b) vinculin staining & view of focal adhesions c) focal adhesions larger than 1 μm2.
Ian Manifacier (848604) +5 more
core +1 more source
Focal adhesions: What's new inside [PDF]
, 2006 The cytoplasmic side of focal adhesions is comprised of large molecular complexes that link transmembrane receptors, such as integrins, to the actin cytoskeleton and mediate signals modulating cell attachment, migration, proliferation, differentiation ...
Lo, Su Hao
core +1 more source
A kinetic model for RNA-interference of focal adhesions [PDF]
, 2013 Background: Focal adhesions are integrin-based cell-matrix contacts that transduce and integrate mechanical and biochemical cues from the environment. They develop from smaller and more numerous focal complexes under the influence of mechanical force and
Hoffmann, Max, Schwarz, Ulrich Sebastian
core +2 more sources
TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility. [PDF]
PLoS ONE, 2015 Cellular migration and contractility are fundamental processes that are regulated by a variety of concerted mechanisms such as cytoskeleton rearrangements, focal adhesion turnover, and Ca2+ oscillations.
Mónica Cáceres +16 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source