Results 41 to 50 of about 14,325,085 (286)

Skin involvement in systemic lymphoma of follicular helper T‐cell origin: A cohort study of 57 patients

JEADV Clinical Practice, 2023
Background Angioimmunoblastic T‐cell lymphoma (AITL) is one of the most frequent peripheral T‐cell lymphomas (PTCL) in western countries. Skin involvement is common and may reveal the malignancy.
Romain Stammler, Maxime Battistella, Julien Calvani, Baptiste Louveau, François Lemonnier, Saskia Ingen‐Housz Oro, Nicolas Ortonne, Jean David Bouaziz, Jacqueline Rivet, Marie‐Dominique Vignon‐Pennamen, David Boutboul, Caroline Ram‐Wolff, Lionel Galicier, Catherine Thieblemont, Pauline Brice, Loïc Renaud, Geraldine Jeudy, Marie Beylot‐Barry, Christian Le Clech, Charlée Nardin, Jean‐Michel Cayuela, Véronique Meignin, Samia Mourah, Martine Bagot, Adèle De Masson, French Study Group on Cutaneous Lymphomas   +25 more
doaj   +1 more source

Precise diagnosis and targeted therapy of nodal T-follicular helper cell lymphoma (T-FHCL)

Frontiers in Oncology, 2023
Nodal T-follicular helper cell lymphoma (T-FHCL) derived from T-follicular helper (Tfh) cell falls into a heterogeneous category of peripheral T-cell lymphoma (PTCL).
Jun Du, Shikai Jin, Minghui Zhang, Xuehang Fu, Jingwen Yang, Liwen Zhang, Zhenwei Chen, Zoufang Huang, Weisong Li, Jian Hou, Ting Wang   +10 more
doaj   +1 more source

Advances in the role of follicular T helper cells in graft versus host diseases

Liver Research, 2017
Graft versus host disease (GVHD) is a refractory complication of allogeneic hematopoietic stem cell transplantation for the treatment of malignant and non-malignant hematopoietic diseases.
Maogen Chen, Xiaohong Lin, Julie Wang, Nancy Olsen, Song Guo Zheng   +4 more
doaj   +1 more source

Plexin B2 and Semaphorin 4C Guide T Cell Recruitment and Function in the Germinal Center

Cell Reports, 2017
Summary: Follicular T helper (TFH) cells orchestrate the germinal center (GC) response locally. TFH localization in GCs is controlled by chemo-guidance cues and antigen-specific adhesion. Here.
Hu Yan, Longyan Wu, Changming Shih, Shiyue Hou, Jingwen Shi, Tianyang Mao, Wenbin Chen, Bhavani Melvin, Robert J. Rigby, Yingjia Chen, Haochen Jiang, Roland H. Friedel, Carola G. Vinuesa, Hai Qi   +13 more
doaj   +1 more source

B Cell Help by CD1d-Rectricted NKT Cells

Antibodies, 2015
B cell activation and antibody production against foreign antigens is a central step of host defense. This is achieved via highly regulated multi-phase processes that involve a variety of cells of both innate and adaptive arms of the immune system.
Livia Clerici, Giulia Casorati, Paolo Dellabona   +2 more
doaj   +1 more source

Regulation of IgE by T follicular helper cells

Journal of Leukocyte Biology, 2020
Abstract Allergies to food and environmental antigens have steeply grown to epidemic proportions. IgE antibodies are key mediators of allergic disease, including life-threatening anaphylaxis. There is now compelling evidence that one of the hallmarks of anaphylaxis-inducing IgE molecules is their high affinity for allergen, and the ...
Uthaman Gowthaman, Jennifer S. Chen, Stephanie C. Eisenbarth   +2 more
openaire   +3 more sources

IL-6 Impairs Vaccine Responses in Neonatal Mice

Frontiers in Immunology, 2018
The inability of infants to mount proper follicular helper T (TFH) cell response renders this age group susceptible to infectious diseases. Initial instruction of T cells by antigen presenting cells and subsequent differentiation into TFH cells are ...
Jiyeon Yang, Jiro Sakai, Shafiuddin Siddiqui, Robert C. Lee, Derek D. C. Ireland, Daniela Verthelyi, Mustafa Akkoyunlu   +6 more
doaj   +1 more source

Th17 effector cells support B bell responses outside of germinal centres [PDF]

, 2012
Th17 cells are pro-inflammatory CD4+T cells, which are important in immune responses against fungal pathogens and extracellular bacteria and have also been implicated in various autoimmune syndromes.
David R Withers, Brewer James M., Benson, RA, David R. Withers, Paola Conigliaro, Agapitos Patakas (120270), Benson, R.A., Iain B McInnes, Patakas, A, David R. Withers (120281), Paul Garside, McInnes Iain B., Paul Garside (21184), Conigliaro, P, Withers, DR, Robert A. Benson, McInnes, I.B., CONIGLIARO, PAOLA, Patakas Agapitos, Benson Robert A., Patakas, A., Conigliaro, P., Withers David R., Agapitos Patakas, Brewer, J.M., Iain B. McInnes (120290), Robert A Benson, Paola Conigliaro (71046), Conigliaro Paola, Garside Paul, Robert A. Benson (120275), Garside, P, Mcinnes, LB, Garside, P., James M. Brewer, Iain B. McInnes, James M Brewer, Withers, D.R., Brewer, JM, James M. Brewer (120295)   +39 more
core   +1 more source

Detection of Mouse Natural Killer T Follicular Helper (NKTFH) Cells by Flow Cytometry

, 2016
Natural killer T follicular helper (NKTFH) cell, a recently identified B-cell helper innate cell population, can be easily missed due to its low frequency and the fact that it only forms upon immunization or infection with glycolipid-containing antigens ...
Garcia De Vinuesa, Maria Carola, Chang, Pheh   +1 more
core   +1 more source

Follicular Helper T Cells: Lineage and Location [PDF]

Immunity, 2009
Follicular helper T (Tfh) cells are the class of effector T helper cells that regulates the step-wise development of antigen-specific B cell immunity in vivo. Deployment of CXCR5+ Tfh cells to B cell zones of lymphoid tissues and stable cognate interactions with B cells are central to the delivery of antigen-specific Tfh cell function.
Fazilleau, Nicolas, Mark, Linda, McHeyzer-Williams, Louise J., McHeyzer-Williams, Michael G.   +3 more
openaire   +2 more sources