Results 61 to 70 of about 14,832,680 (288)
Follicular helper T cell in immunity and autoimmunity [PDF]
Brazilian Journal of Medical and Biological Research, 2016 The traditional concept that effector T helper (Th) responses are mediated by Th1/Th2 cell subtypes has been broadened by the recent demonstration of two new effector T helper cells, the IL-17 producing cells (Th17) and the follicular helper T cells (Tfh).
Mesquita Jr, D. +6 more
openaire +6 more sources
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Cell Reports, 2020 Summary: T follicular helper (Tfh) cells are fundamental for B cell selection and antibody maturation in germinal centers. Circulating Tfh (cTfh) cells constitute a minor proportion of the CD4+ T cells in peripheral blood, but their clonotypic ...
Elena Brenna +13 more
doaj +1 more source
Shared and distinct roles of T peripheral helper and T follicular helper cells in human diseases [PDF]
, 2021 The interactions of CD4⁺ T cells and B cells are fundamental for the generation of protective antibody responses, as well as for the development of harmful autoimmune diseases.
Hiroyuki Yoshitomi +3 more
core +1 more source
FEBS Open Bio, EarlyView.Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
B Cell Help by CD1d-Rectricted NKT Cells
Antibodies, 2015 B cell activation and antibody production against foreign antigens is a central step of host defense. This is achieved via highly regulated multi-phase processes that involve a variety of cells of both innate and adaptive arms of the immune system.
Livia Clerici +2 more
doaj +1 more source
Frontiers in Immunology, 2021 Follicular helper T (TFH) cells are specialized CD4+ helper T cells that provide help to B cells in humoral immunity. However, the molecular mechanism underlying generation of TFH cells is incompletely understood.
Lingtao Yang +12 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao +5 more
wiley +1 more source
New Territory for T Follicular Helper Cells [PDF]
Immunity, 2013 T follicular helper (Tfh) cells have been thrust into the limelight since the recent discovery of their unique developmental program. Exciting new insights into the regulation of Tfh development, migration, and function were presented at the first Gordon Conference on Tfh cells held in Hong Kong and summarized here.
Vinuesa, Carola +2 more
openaire +3 more sources
Marginal zone B cells: virtues of innate-like antibody-producing lymphocytes [PDF]
, 2013 Protective responses to microorganisms involve the nonspecific but rapid defence mechanisms of the innate immune system, followed by the specific but slow defence mechanisms of the adaptive immune system. Located as sentinels at the interface between the
Cols, M +5 more
core +1 more source