Results 41 to 50 of about 14,832,680 (288)
FACS Staining for Follicular Helper T Cells
Bio-Protocol, 2012 Germinal center is the primary site for B cells to undergo somatic hypermutation and class switching. A recently discovered subset of T cells known as T follicular helper (TFH) cells are essential for germinal center reaction and thus have been the ...
Zheng Liu
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Follicular Helper T Cells: Lineage and Location [PDF]
Immunity, 2009 Follicular helper T (Tfh) cells are the class of effector T helper cells that regulates the step-wise development of antigen-specific B cell immunity in vivo. Deployment of CXCR5+ Tfh cells to B cell zones of lymphoid tissues and stable cognate interactions with B cells are central to the delivery of antigen-specific Tfh cell function.
Fazilleau, Nicolas +3 more
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Immunological mechanism of IgG4-related disease
Journal of Translational Autoimmunity, 2020 IgG4-related disease (IgG4-RD) is an immune-mediated inflammatory disorder in multiple organs, characterized by abundant infiltration of IgG4-positive plasmacytes and fibrosis in the involved organs.
Changyan Liu, Panpan Zhang, Wen Zhang
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Signaling Pathways in T Follicular Helper Cells [PDF]
The Journal of Immunology, 2010 Abstract Th cell functional subsets have unique transcriptional programs that form the molecular basis for T cell differentiation and functions. T follicular helper (TFH) cells have emerged as the main providers of T cell help to B cells during the germinal center (GC) reaction, where B cells undergo selection events through ...
Julia, Rolf +2 more
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Regulation of IgE by T follicular helper cells
Journal of Leukocyte Biology, 2020 Abstract Allergies to food and environmental antigens have steeply grown to epidemic proportions. IgE antibodies are key mediators of allergic disease, including life-threatening anaphylaxis. There is now compelling evidence that one of the hallmarks of anaphylaxis-inducing IgE molecules is their high affinity for allergen, and the ...
Uthaman Gowthaman +2 more
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CAR NK Cell Therapy for T Follicular Helper Cells [PDF]
, 2020 T follicular helper (TFH) cells are associated with the development of both autoimmune disease and T cell malignancies. In this issue, Reighard et al.,1 describe the design of PD-L1 chimeric antigen receptor (CAR) NK cells that effectively target and ...
King, C ; https://orcid.org/
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Detection of Mouse Natural Killer T Follicular Helper (NKTFH) Cells by Flow Cytometry
, 2016 Natural killer T follicular helper (NKTFH) cell, a recently identified B-cell helper innate cell population, can be easily missed due to its low frequency and the fact that it only forms upon immunization or infection with glycolipid-containing antigens ...
Garcia De Vinuesa, Maria Carola +1 more
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Cells, 2023 Humoral immune response is important in fighting pathogens by the production of specific antibodies by B cells. In germinal centers, T follicular helper (TFH) cells provide important help to B-cell antibody production but also contribute to HIV ...
Bradley Salvatore +8 more
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Plexin B2 and Semaphorin 4C Guide T Cell Recruitment and Function in the Germinal Center
Cell Reports, 2017 Summary: Follicular T helper (TFH) cells orchestrate the germinal center (GC) response locally. TFH localization in GCs is controlled by chemo-guidance cues and antigen-specific adhesion. Here.
Hu Yan +13 more
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Regulatory T cell-mediated control of chronic inflammation
Frontiers in Immunology, 2012 Autoimmune inflammation including autoantibody-mediated inflammation is responsible for the lethal organ damage that occurs during autoimmune diseases.
Keishi eFujio +3 more
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