Results 21 to 30 of about 14,832,680 (288)
Advances in the role of follicular T helper cells in graft versus host diseases
Liver Research, 2017 Graft versus host disease (GVHD) is a refractory complication of allogeneic hematopoietic stem cell transplantation for the treatment of malignant and non-malignant hematopoietic diseases.
Maogen Chen +4 more
doaj +2 more sources
Follicular regulatory T cells eliminate HIV-1-infected follicular helper T cells in an IL-2 concentration dependent manner [PDF]
Frontiers in Immunology, 2022 Follicular helper CD4+ T cells (TFH) are highly permissive to HIV and major foci of virus expression in both untreated and treated infection. Follicular regulatory CD4+ T cells (TFR) limit TFH numbers and function in vitro and in vivo.
Matthew T. Ollerton +7 more
doaj +2 more sources
T helper1/T helper2 cells and resistance/susceptibility to Leishmania infection : is this paradigm still relevant? [PDF]
, 2012 Work in large part on Leishmania major in the 1980s identified two distinct apparently counter-regulatory CD4 T cell populations, T helper (h)1 and Th2, that controlled resistance/susceptibility to infection respectively.
Brombacher, F. +5 more
core +4 more sources
Human follicular helper T lymphocytes critical players in antibody responses
Einstein (São Paulo), 2021 Follicular helper T lymphocytes are a subpopulation of CD4+ T lymphocytes initially identified in germinal centers of follicles found in secondary lymphoid organs. The primary function of follicular helper T lymphocytes is to help B lymphocytes’ antibody
Giovana Toledo Alonso +2 more
doaj +2 more sources
T follicular helper cells in cancer
Trends in Cancer, 2023 T follicular helper (Tfh) cells provide essential help to B cells for effective antibody-mediated immune responses. Although the crucial function of these CD4+ T cells in infection and vaccination is well established, their involvement in cancer is only beginning to emerge.
Nicolás Gutiérrez-Melo +1 more
openaire +2 more sources
Frontiers in Immunology, 2023 T follicular helper cells comprise a specialized, heterogeneous subset of immune-competent T helper cells capable of influencing B cell responses in lymphoid tissues.
Julien Subburayalu +2 more
doaj +1 more source
T Follicular Helper Cells in Transplantation [PDF]
Transplantation, 2016 The recently described T follicular helper (Tfh) cell is required for the production of high affinity antibody. After contact with follicular dendritic cells, Tfh cells move into the germinal centre and provide help to B cells both by direct B cell-T cell interaction and production of IL-21.
Giles Desmond, Walters +1 more
openaire +4 more sources
The dysfunction of T follicular helper cells [PDF]
Current Opinion in HIV and AIDS, 2014 T follicular helper (Tfh) cells play a critical role as providers of B-cell help and dysfunction in Tfh/B-cell interactions can lead to autoimmunity or immunodeficiency. These observations have generated a great deal of interest in understanding how these cells are affected during HIV infection and how their functional changes might affect antibody ...
Cubas R, Perreau M
openaire +3 more sources
TFH cells in systemic sclerosis
Journal of Translational Medicine, 2021 Systemic sclerosis is an autoimmune disease characterized by excessive dermal fibrosis with progression to internal organs, vascular impairment and immune dysregulation evidenced by the infiltration of inflammatory cells in affected tissues and the ...
Pauline Beurier +8 more
doaj +1 more source