Results 51 to 60 of about 5,776,856 (311)

Guidance on methodological principles and scientific methods to be taken into account when establishing Reference Points for Action (RPAs) for non-allowed pharmacologically active substances present in food of animal origin [PDF]

EFSA Journal, 2013
EFSA was asked by the European Commission to deliver a Scientific Opinion on guidance on methodological principles and scientific methods to be taken into account when establishing Reference Points for Action (RPAs) for non-allowed pharmacologically ...
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj   +1 more source

Brain damage and behavioural disorders in fish induced by plastic nanoparticles delivered through the food chain

Scientific Reports, 2017
The tremendous increases in production of plastic materials has led to an accumulation of plastic pollution worldwide. Many studies have addressed the physical effects of large-sized plastics on organisms, whereas few have focused on plastic ...
Karin Mattsson, Elyse V. Johnson, A. Malmendal, S. Linse, L. Hansson, T. Cedervall   +5 more
semanticscholar   +1 more source

Mercury biomagnification in an ichthyic food chain of an amazon floodplain lake (Puruzinho Lake): Influence of seasonality and food chain modeling.

Ecotoxicology and Environmental Safety, 2020
Mercury (Hg) biomagnification in fish food chains is a relevant subject due to the high fish consumption of the Amazonian population and the high toxicity of this metal.
L. S. Azevedo, I. A. Pestana, M. G. Almeida, Adriely Ferreira da Costa Nery, W. Bastos, Cristina Maria Magalhães Souza   +5 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Data-Driven Early Warning Approach for Antimicrobial Resistance Prediction–Anomaly Detection Based on High-Level Indicators

Veterinary Sciences
Environmental conditions are increasingly recognized as important contributors to the emergence and spread of antimicrobial resistance (AMR), yet early detection of high-risk situations remains difficult.
Szilveszter Csorba, Krisztián Vribék, Máté Farkas, Miklós Süth, Orsolya Strang, Andrea Zentai, Zsuzsa Farkas   +6 more
doaj   +1 more source

Remarks on food chain dynamics [PDF]

Mathematical Biosciences, 1996
The main modes of behavior of a food chain model composed of logistic prey and Holling type II predator and superpredator are discussed in this paper. The study is carried out through bifurcation analysis, alternating between a normal form approach and numerical continuation.
KUZNETSOV Y. A., RINALDI, SERGIO
openaire   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Antimicrobial use and Escherichia coli resistance patterns in Hungarian pig farms: a data-driven farm-level analysis

Scientific Reports
Antimicrobial resistance (AMR) poses a critical challenge to both human and veterinary medicine, with pig production recognized as one of the major contributor due to intensive antimicrobial usage (AMU).
Krisztián Vribék, Máté Farkas, Szilveszter Csorba, Miklós Süth, László Gombos, Ádám Kerek, Zoltán Somogyi, Ákos Jerzsele, Zsuzsa Farkas   +8 more
doaj   +1 more source