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Regulatory T cell dysfunction and immunotherapeutic breakthroughs in type 1 diabetes. [PDF]

open access: yesFront Endocrinol (Lausanne)
Zhou KJ   +6 more
europepmc   +1 more source
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Polymorphism of the ovine FOXP3 gene (FOXP3)

Veterinary Immunology and Immunopathology, 2011
FOXP3 is a transcription factor predominantly expressed in CD4(+) CD25(+) thymocytes and CD4(+) CD25(+) peripheral T cells. It has been reported that variation in the FOXP3 gene (FOXP3) could cause impaired immune regulation. Using PCR-SSCP, variation in exon 4, exon 9-10 and exon 13-14 of ovine FOXP3, covering three functional domains (a proline rich ...
Guo, Yang   +2 more
openaire   +2 more sources

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