Results 51 to 60 of about 84,275 (305)
, 2013 A) Imaged areas of the embryo – the region localised anteriorly to the cephalic furrow shows lower levels of morphogenetic activity whilst the posterior region shows high levels of morphogenetic activity.
João Firmino (392682) +2 more
core +1 more source
Advanced Science, EarlyView.Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu +14 more
wiley +1 more source
Angewandte Chemie, EarlyView.A coumarin‐based dual‐emission fluorophore was designed to visualize the maturation of protein liquid droplets. Upon covalent conjugation to droplet‐forming proteins, ratiometric fluorescence imaging allowed real time monitoring of droplet maturation. This probe is applicable to the analysis of droplet formation and maturation mechanisms, as well as to
Tomoya Yamamoto +6 more
wiley +2 more sources
Effect of heat treatment on phenolic content and antioxidant activity of peanut (Arachis hypogaea L.) extracts [PDF]
مجلة جامعة الانبار للعلوم الصرفةPeanuts are rich in various bioactive compounds, including total phenolics and total flavonoids. The aim of this study is to evaluate the effects of heating on total phenolic content, total flavonoid content, and antioxidant activity in peanut (Arachis ...
Eman Mohamed +3 more
doaj +1 more source
Cdc10 FRAP summary statistics.
, 2015 * P < 0.0001 (determined by two-tailed t tests)Cdc10 FRAP summary statistics.
Marie-Elisabeth Bougnoux (493284) +12 more
core +1 more source
Advanced Science, EarlyView.PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu +12 more
wiley +1 more source
Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis
Advanced Science, EarlyView.In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley +1 more source
, 2012 COS-7 cells were transfected with the indicated constructs or left untransfected and labeled with Alexa546-CTxB or DiIC16. FRAP was performed at 37°C using a 4.1 µm diameter bleach spot. (A) Representative images of Alexa546-CTxB during a FRAP experiment.
Anne K. Kenworthy (171459) +1 more
core +1 more source
Advanced Science, EarlyView.HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li +13 more
wiley +1 more source