Results 81 to 90 of about 911 (170)

Fucosylated and Sulfated Glycans Investigated using Cryogenic Infrared Spectroscopy [PDF]

open access: yes, 2022
Unusual monosaccharides (fucose), covalent modifications of glycans (sulfation) and terminal sequences play important biological roles in physiology and pathology of living organisms.
Lettow, M.
core  

Genome‐Wide Association Studies of Polysaccharides, Collagen, and Saponin Traits in the Sea Cucumber Apostichopus japonicus

open access: yesAquaculture Research, Volume 2025, Issue 1, 2025.
Apostichopus japonicus is a commercially important marine species known for its high nutritional value and a range of bioactive compounds, including polysaccharides, collagen, and saponins. In this study, a genome‐wide association study (GWAS) was carried out on 143 A. japonicus individuals.
Yongjie Wang   +15 more
wiley   +1 more source

Sulfated Glycans Inhibit the Interaction of MERS-CoV Receptor Binding Domain with Heparin

open access: yesViruses
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus with high contagion and mortality rates. Heparan sulfate proteoglycans (HSPGs) are ubiquitously expressed on the surface of mammalian cells.
Jiyuan Yang   +12 more
doaj   +1 more source

Specific sulfation and glycosylation - a structural combination for the anticoagulation of marine carbohydrates

open access: yesFrontiers in Cellular and Infection Microbiology, 2014
Based on considered achievements of the last 25 years, specific combinations of sulfation patterns and glycosylation types have been proved to be key structural players for the anticoagulant activity of certain marine glycans.
Vitor Hugo Pomin   +1 more
doaj   +1 more source

A biological guide to glycosaminoglycans: current perspectives and pending questions

open access: yesThe FEBS Journal, Volume 291, Issue 15, Page 3331-3366, August 2024.
Mammalian glycosaminoglycans, except hyaluronan, are sulfated polysaccharides that are covalently attached to core proteins to form proteoglycans. They contribute to the organization of the extracellular matrix and are displayed at the cell surface where they regulate the availability and activity of cytokines and growth factors and cell signaling ...
Sylvie Ricard‐Blum   +12 more
wiley   +1 more source

Isolation and composition analysis of bioactive glycosaminoglycans from whelk [PDF]

open access: yes, 2018
Glycosaminoglycans (GAGs) are found covalently attached to proteins, which create conjugates known as proteoglycans. GAGs have remarkable biological activity as co-receptors for a variety of growth factors, cytokines, and chemokines.
Khurshid, CA, Pye, DA
core   +2 more sources

Postoperative tumor treatment strategies: From basic research to clinical therapy

open access: yesVIEW, Volume 5, Issue 3, June 2024.
The latest research on the molecular mechanism of tumor and clinical treatment for postoperative recurrence of tumors has been introduced. This review focuses on the emerging technologies used for postoperative tumor treatment in recent years in terms of functional classification. Abstract Despite progression in advanced treatments for malignant tumors,
Minna Xiao   +7 more
wiley   +1 more source

Sea Cucumbers Metabolites as Potent Anti-Cancer Agents

open access: yesMarine Drugs, 2015
Sea cucumbers and their extracts have gained immense popularity and interest among researchers and nutritionists due to their nutritive value, potential health benefits, and use in the treatment of chronic inflammatory diseases.
Naveena B. Janakiram   +2 more
doaj   +1 more source

Molecular analysis of the extracellular microenvironment: from form to function

open access: yesFEBS Letters, Volume 598, Issue 6, Page 602-620, March 2024.
This review provides a thorough background on the complex structure and function of the major proteins in the extracellular proteome. Analytical challenges that result from these complex structures are detailed followed by current techniques and strategies for spatially profiling the extracellular microenvironment.
Jade K. Macdonald   +3 more
wiley   +1 more source

Glycan Engineering for Cell and Developmental Biology [PDF]

open access: yes, 2016
Cell-surface glycans are a diverse class of macromolecules that participate in many key biological processes, including cell-cell communication, development, and disease progression.
Griffin, Matthew E.   +1 more
core   +1 more source

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