Results 91 to 100 of about 13,321 (212)

Molecular recognition in plant root endosymbiosis

The Plant Journal, Volume 127, Issue 3, August 2026.
SUMMARY Root endosymbiosis is one of the most intimate types of plant–microbe interactions in which a symbiont is hosted within a living plant cell. In this symbiosis, nitrogen‐fixing bacteria and arbuscular mycorrhizal fungi support plant nutrient provisioning in exchange for carbohydrates and lipids.
Tora Fougner‐Økland, Maria Spezzati, Katarzyna Parys   +2 more
wiley   +1 more source

[Role of Fucosylation in Cancer].

Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2016
Fucosylation is one of the most important glycosylation in mamal, involving biosynthesis of blood H antigen and Lewis antigen, selectin mediated intravasion and homing of leukocyte, host-microbe interactions, modification of signaling. Alterations in the expression of fucosylated oligosaccharides have been observed in several cancer, playing a role in ...
Kun ZHANG, Hong WANG
openaire   +2 more sources

Protein O-Fucosyltransferases: Biological Functions and Molecular Mechanisms in Mammals

Molecules
Domain-specific O-fucosylation is an unusual type of glycosylation, where the fucose is directly attached to the serine or threonine residues in specific protein domains via an O-linkage.
Huilin Hao, Benjamin M. Eberand, Mark Larance, Robert S. Haltiwanger   +3 more
doaj   +1 more source

Impact of Acetylated and Non-Acetylated Fucose Analogues on IgG Glycosylation

Antibodies, 2019
The biological activity of therapeutic antibodies is highly influenced by their glycosylation profile. A valuable method for increasing the cytotoxic efficacy of antibodies, which are used, for example, in cancer treatment, is the reduction of core ...
Martina Zimmermann, Janike Ehret, Harald Kolmar, Aline Zimmer   +3 more
doaj   +1 more source

Nicotinamide Reverses the Warburg Effect in CHO Cell Culture

Biotechnology and Bioengineering, Volume 123, Issue 7, Page 1902-1915, July 2026.
ABSTRACT The Warburg effect, the preferential conversion of glucose‐derived pyruvat to lactate despite available oxygen, is a key feature of Chinese hamster ovary (CHO) cell culture. Lactate accumulation in recombinant protein‐producing cell culture is an inefficient usage of glucose, as well as being deleterious to cells.
James Morrissey, Ayca Cankorur‐Cetinkaya, Luigi Grassi, Annie J. Harwood‐Stamper, Jonathan Welsh, Ryte Poskute, Kasia Kozakowska‐McDonnell, Cleo Kontoravdi   +7 more
wiley   +1 more source

Exploring fucosylation in lung cancer: Mechanisms, diagnosis, and therapeutic strategies

Advances in Biomarker Sciences and Technology
Lung cancer remains a global health crisis, responsible for significant morbidity and mortality. Late-stage diagnosis often limits treatment options and patient survival.
Saima Rafique, Wei Ge, Ziyuan Gao, Yan Chen, Jun Xia, Junhong Jiang, Shuang Yang   +6 more
doaj   +1 more source

N-Glycomic and Transcriptomic Changes Associated with CDX1 mRNA Expression in Colorectal Cancer Cell Lines

Cells, 2019
The caudal-related homeobox protein 1 (CDX1) is a transcription factor, which is important in the development, differentiation, and homeostasis of the gut.
Stephanie Holst, Jennifer L. Wilding, Kamila Koprowska, Yoann Rombouts, Manfred Wuhrer   +4 more
doaj   +1 more source

Fucosylated Human Milk Oligosaccharides and N-Glycans in the Milk of Chinese Mothers Regulate the Gut Microbiome of Their Breast-Fed Infants during Different Lactation Stages

mSystems, 2018
The milk glycobiome has a significant impact on the gut microbiota of infants, which plays a pivotal role in health and development. Fucosylated human milk oligosaccharides (HMOs) and N-glycans on milk proteins are beneficial for the development of ...
Yaqiang Bai, Jia Tao, Jiaorui Zhou, Qingjie Fan, Man Liu, Yuqi Hu, Yao Xu, Lilong Zhang, Jieli Yuan, Wenzhe Li, Xiaolei Ze, Patrice Malard, Zhimou Guo, Jingyu Yan, Ming Li   +14 more
doaj   +1 more source

Stable overexpression of native and artificial miRNAs for the production of differentially fucosylated antibodies in CHO cells

Engineering in Life Sciences
Cell engineering strategies typically rely on energy‐consuming overexpression of genes or radical gene‐knock out. Both strategies are not particularly convenient for the generation of slightly modulated phenotypes, as needed in biosimilar development of ...
Patrick Schlossbauer, Lukas Naumann, Florian Klingler, Madina Burkhart, René Handrick, Kathrin Korff, Christian Neusüß, Kerstin Otte, Friedemann Hesse   +8 more
doaj   +1 more source

Applying Acylated Fucose Analogues to Metabolic Glycoengineering

Bioengineering, 2015
Manipulations of cell surface glycosylation or glycan decoration of selected proteins hold immense potential for exploring structure-activity relations or increasing glycoprotein quality.
Julia Rosenlöcher, Verena Böhrsch, Michael Sacharjat, Véronique Blanchard, Christoph Giese, Volker Sandig, Christian P. R. Hackenberger, Stephan Hinderlich   +7 more
doaj   +1 more source