Results 31 to 40 of about 7,198,263 (194)
Fucosyltransferase activities in human lymphocytes and granulocytes Blood group H-gene-specified α-2-L-fucosyltransferase is a discriminatory marker of peripheral blood lymphocytes [PDF]
, 1983 Human lymphocytes and granulocytes were examined for blood group H-gene-specified α-2-L-fucosyl-transferase, α-3-L-fucosyltransferase and blood group Le-gene-specified α-4-L-fucosyltransferase.
Ball, M.Geraldine +5 more
core +1 more source
Microbiota Depletion Promotes Human Rotavirus Replication in an Adult Mouse Model
Biomedicines, 2021 Intestinal microbiota-virus-host interaction has emerged as a key factor in mediating enteric virus pathogenicity. With the aim of analyzing whether human gut bacteria improve the inefficient replication of human rotavirus in mice, we performed fecal ...
Roberto Gozalbo-Rovira +8 more
doaj +1 more source
O-Glycosylation of thrombospondin type 1 repeats : identification and characterisation of β1,3-glucosyltransferase [PDF]
, 2008 Rare types of protein glycosylation often occur in a domain-specific manner required for important biological functions (Okajima et al. 2008). O-linked fucosylation, where the fucose is linked directly to the hydroxyl groups of serine or threonine ...
Keusch, Krisztina
core +1 more source
Clinical Medicine Insights: Oncology, 2023 Background: The incidence of intrahepatic cholangiocarcinoma (ICC) is increasing globally, and its prognosis has not improved substantially in recent years. Understanding the pathogenesis of ICC may provide a theoretical basis for its treatment.
Jingheng Guo +7 more
doaj +1 more source
Genetic engineering strategies to prevent the effects of antibody and complement on xenogeneic chondrocytes [PDF]
European Cells & Materials, 2015 Advances in animal transgenesis may allow using xenogeneic chondrocytes in tissue-engineering applications for clinical cartilage repair. Porcine cartilage is rejected by humoral and cellular mechanisms that could be overcome by identifying key molecules
R Sommaggio +5 more
doaj +1 more source
Histology and histopathology, 2016 The aim of this study was to compare the expression of fucosyltransferase 8 (FUT8) in breast cancer tissue and to investigate the relationship between this marker with tumor progression and its applicability to differential diagnosis. An immunohistochemical study was performed for FUT8 using the tissue microarray technique.
Yue, Liling +6 more
openaire +3 more sources
The Dual Role and Clinical Potential of Core Fucosylation in Liver Diseases
Shengwu huaxue yu shengwu wuli jinzhanCore fucosylation, catalyzed exclusively by fucosyltransferase 8 (FUT8), is an evolutionarily conserved post-translational modification that has emerged as a central regulatory hub linking liver homeostasis, chronic disease progression, and malignant ...
LEI Zi-Han +4 more
doaj +1 more source
O-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand function. [PDF]
PLoS ONE, 2014 Fucosylation of Epidermal Growth Factor-like (EGF) repeats by protein O-fucosyltransferase 1 (POFUT1 in vertebrates, OFUT1 in Drosophila) is pivotal for NOTCH function.
Julia Müller +5 more
doaj +1 more source
Pathogens, 2021 Helicobacter pylori (H. pylori) adhesion to human gastric epithelial cells is closely linked with fucosylated glycans. Therefore, investigation of fucosylation in the interaction of gastric epithelial cells with H. pylori is critical.
Ruyue Fan +12 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro +25 more
wiley +1 more source