Results 51 to 60 of about 74,907,945 (195)

Substrate Specificity of Fucosyltransferase Purified from Human Parotid Saliva

, 1987
The purified fucosyltransferase from human parotid saliva was shown to transfer fucose from GDP-fucose onto the oligosaccharide chains containing the Galβl→3GlcNAc or Gal β 1→4GlcNAc/Glc sequences.
H. Tamagawa, K. Iwakura, S. Shizukuishi, A. Amano, A. Tsunemitsu   +4 more
core   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Microbiota From Human Infants Consuming Secretors Mothers' Milk Affects Murine Intestinal Motility and Enteric Nervous System Development in a Sex‐Dependent Manner

Neurogastroenterology &Motility, Volume 38, Issue 11, November 2026.
Early feeding influences the gut microbiome, which programs gut neuronal function later in life. Transferring gut bacteria from breastfed and formula‐fed infants into germ‐free mice revealed sex‐specific effects. Microbiota from infants of secretor mothers increased transit efficiency and nitrergic neurons in the large intestine of female mice, while ...
Bharath K. Kumar, Valentina Caputi, Kirandeep K. Gill, Bindu Nanduri, Tanya Leroith, Renee Fox, Fernanda Rosa, Joshua M. Lyte, Laxmi Yeruva   +8 more
wiley   +1 more source

Helicobacter pylori serologic status has no influence on the association between fucosyltransferase 2 polymorphism (FUT2 461 G->A) and vitamin B-12 in Europe and West Africa

, 2012
Genomewide association studies have shown a relation between plasma vitamin B-12 concentration and the 461G→A polymorphism of fucosyltransferase 2 (FUT2), a gene associated with susceptibility to Helicobacter pylori ...
Jean-Pierre Bronowicki, Justine Paoli, Emile Amouzou, Céline Chery, Guido Anello, Paolo Bosco, Abderrahim Oussalah, Cyril Besseau, Maurizzio Elia, Philippe Gerard, Laurent Peyrin-Biroulet, Patrice Hodonou Avogbe, Ambaliou Sanni, Jean-Louis Guéant, Romano, Antonino, Antonino Romano, Nicodème Chabi, Elise Jeannesson, Rosa-Maria Guéant-Rodriguez   +18 more
core   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, Volume 600, Issue 20, Page 3051-3072, October 2026.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Helicobacter hepaticus Hh0072 gene encodes a novel α1-3-fucosyltransferase belonging to CAZy GT11 family

, 2010
Lewis x (Lex) and sialyl Lewis x (SLex)-containing glycans play important roles in numerous physiological and pathological processes. The key enzyme for the final step formation of these Lewis antigens is α1-3-fucosyltransferase. Here we report molecular
Huang, Shengshu, Lau, Kam, Wang, Peng G, Sugiarto, Go, Li, Yanhong, Zhang, Lei, Yu, Hai, Chen, Xi, Ding, Li, Cheng, Jiansong, Thon, Vireak   +10 more
core   +1 more source

Glycoproteomic Signatures of IgG Subclass N‐Glycosylation Reveal Molecular Endotypes in Idiopathic Inflammatory Myopathies

MedComm, Volume 7, Issue 10, October 2026.
• EThcD‐sceHCD‐MS/MS and updated PANDA software decode IgG N‐glycosylation in IIMs. • Unsupervised clustering reveals three novel glyco‐endotypes matching clinical phenotypes. • A seven‐glycopeptide model enables robust endotype prediction beyond conventional subtypes.
Tong Wu, Yanhong Li, Yingying Ling, Yinlan Wu, Jing Zhao, Lu Cheng, Chunyu Tan, Yi Zhang, Yong Zhang, Yi Liu   +9 more
wiley   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, Volume 81, Issue 10, Page 3439-3452, October 2026.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Quantitative glycoproteomics analysis identifies novel FUT8 targets and signaling networks critical for breast cancer cell invasiveness

Breast Cancer Research, 2022
Background We recently showed that fucosyltransferase 8 (FUT8)-mediated core fucosylation of transforming growth factor-β receptor enhances its signaling and promotes breast cancer invasion and metastasis.
Cheng-Fen Tu, Fu-An Li, Ling-Hui Li, Ruey-Bing Yang   +3 more
doaj   +1 more source

Pathophysiology of the gut–eye axis in a Sjögren's disease‐like dry eye mouse model: An exploratory evaluation of dietary heat‐treated Enterococcus faecalis FK‐23

Experimental Physiology, Volume 111, Issue 10, Page 4507-4524, 1 October 2026.
Abstract Sjögren's disease is an autoimmune disease characterized by severe dry eye, but its pathophysiology remains unclear. Non‐obese diabetic (NOD) mice develop Sjögren's disease‐like dry eye prior to the onset of diabetes. Although intestinal immune abnormalities precede diabetes in NOD mice, their relationship to dry eye remains poorly understood.
Kenji Goto, Shigekazu Takemura, Yukiko Minamiyama, Toshikazu Yoshikawa   +3 more
wiley   +1 more source