Results 61 to 70 of about 14,436 (200)

High expression FUT1 and B3GALT5 is an independent predictor of postoperative recurrence and survival in hepatocellular carcinoma. [PDF]

, 2017
Cancer may arise from dedifferentiation of mature cells or maturation-arrested stem cells. Previously we reported that definitive endoderm from which liver was derived, expressed Globo H, SSEA-3 and SSEA-4.
Ho, Ming-Yi, Hsieh, Chung-Bao, Huang, Yen-Lin, Hung, Jung-Tung, Hung, Tsai-Hsien, Kuo, Huan-Hsien, Lin, Ruey-Jen, Lo, Fei-Yun, Yeh, Chau-Ting, Yu, Alice L, Yu, John   +10 more
core   +3 more sources

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

Core Fucosylation of Intestinal Epithelial Cells Protects Against Salmonella Typhi Infection via Up-Regulating the Biological Antagonism of Intestinal Microbiota

Frontiers in Microbiology, 2020
The fucosylated carbohydrate moieties on intestinal epithelial cells (IECs) are involved in the creation of an environmental niche for commensal and pathogenic bacteria. Core fucosylation catalyzed by fucosyltransferase 8 (Fut8) is the major fucosylation
Sijia Hao, Qingjie Fan, Yaqiang Bai, Hui Fang, Jiaorui Zhou, Tomohiko Fukuda, Jianguo Gu, Ming Li, Wenzhe Li   +8 more
doaj   +1 more source

Sec1 regulates intestinal mucosal immunity in a mouse model of inflammatory bowel disease

BMC Immunology, 2023
Inflammatory bowel disease (IBD) is a common immune-mediated condition with its molecular pathogenesis remaining to be fully elucidated. This study aimed to deepen our understanding of the role of FUT2 in human IBD, by studying a new surrogate gene Sec1,
Jing Cai, Hao Wu, Chenxing Wang, Yujiao Chen, Dingli Zhang, Shiwei Guan, Beilei Fu, Yingli Jin, Cao Qian   +8 more
doaj   +1 more source

Profiling of aminoxyTMT-labeled bovine milk oligosaccharides reveals substantial variation in oligosaccharide abundance between dairy cattle breeds. [PDF]

, 2019
Free milk oligosaccharides are bioactive molecules that function as prebiotics and prevent infections that commonly afflict developing infants. To date, few publications have examined the factors affecting bovine milk oligosaccharide production among ...
Barile, Daniela, Colet, Emeline, Duchene, Chloe, Larsen, Lotte Bach, Poulsen, Nina A, Robinson, Randall C   +5 more
core   +2 more sources

Multiomics Research Strategies in Cancer: A Growing and Innovative Field

MedComm, Volume 7, Issue 4, April 2026.
This review highlights multiomics strategies in cancer research, focusing on integration methods from genomics to microbiomics. Using colorectal cancer as a key example, it discusses biomarker discovery, data integration via deep learning, and the roles of single‐cell and spatial omics.
Zhenhua Du, Xiaomei Liu, Zhi Lv, Bengang Wang, Yu Xia, Wala Abduljabbar Mohammed Al‐Duais, Lirong Yan, Fuqiang Zhang, Yanke Li   +8 more
wiley   +1 more source

FUT8 Is a Critical Driver of Prostate Tumour Growth and Can Be Targeted Using Fucosylation Inhibitors

Cancer Medicine
Background An unmet clinical need requires the discovery of new treatments for men facing advanced prostate cancer. Aberrant glycosylation is a universal feature of cancer cells and plays a key role in tumour growth, immune evasion and metastasis ...
Kayla Bastian, Margarita Orozco‐Moreno, Huw Thomas, Kirsty Hodgson, Eline A. Visser, Emiel Rossing, Johan F. A. Pijnenborg, Nienke Eerden, Laura Wilson, Hasvini Saravannan, Oliver Hanley, Grace Grimsley, Fiona Frame, Ziqian Peng, Bridget Knight, Paul McCullagh, John McGrath, Malcolm Crundwell, Lorna Harries, Norman J. Maitland, Rakesh Heer, Ning Wang, Ethan D. Goddard‐Borger, Ramon Hurtado Guerrero, Thomas J. Boltje, Richard R. Drake, Emma Scott, David J. Elliott, Jennifer Munkley   +28 more
doaj   +1 more source

Trafficking and localization studies of recombinant α1,3-fucosyltransferase VI stably expressed in CHO cells [PDF]

, 2017
Peripheral α1,3-fucosylation of glycans occurs by the action of either one of five different α1,3-fucosyltransferases (Fuc-Ts) cloned to date. Fuc-TVI is one of the α1,3-fucosyltransferases which is capable to synthesize selectin ligands.
Berger, Eric G., Borsig, Lubor, Bowen, Benjamin R., Katopodis, Andreas G.   +3 more
core  

Will xenotransplantation ever be feasible? [PDF]

, 1998
In several recent conferences, the principal questions have been whether xenotransplantation technology should be encouraged and, if so, how it should be regulated.
Demetris, AJ, Fung, J, Murase, N, Rao, AS, Starzl, TE   +4 more
core   +1 more source

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

Advanced Science, Volume 13, Issue 13, 3 March 2026.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou, Xianfei Wang, Teng Ben, Chunping Zhu, Xinlong Lin, Yinmu Li, Xinyue Zhang, Yeling Chen, Yuchen Xuan, Huaiwen Chen, Ke Liu, Fang Wu, Yuexin Ren, Gao Tan   +13 more
wiley   +1 more source