Results 191 to 200 of about 24,047 (218)

Lysimachiae Herba Modulates FXR to Alleviate Cholestatic Liver Injury: Insights from Serum Pharmacochemistry and Experimental Validation. [PDF]

Curr Issues Mol Biol
Zhao W, Yu B, Li C, Li J, Huang H, Cao W.   +5 more
europepmc   +1 more source

Aging-driven metabolic abnormalities remodel intercellular communication through the gut-liver-heart axis and may promote coronary artery disease: the key role of bile acid metabolism. [PDF]

Front Immunol
Chen W, Sun Y, Meng CF, Wu ST, Jiang XY, Meng XM, Wang QF.   +6 more
europepmc   +1 more source

The gut-liver axis: microbial mechanisms and therapeutic implications in MAFLD. [PDF]

Front Cell Infect Microbiol
Xue L, Wang H, Shan B, Li C, Chen H, Yu C, Xia C, Zhang H.   +7 more
europepmc   +1 more source

Dietary Supplementation of Glutamate Alleviates LPS-Induced Intestinal Injury Associated with m⁶A Modification of SLC10A2 in Weaned Piglets. [PDF]

Animals (Basel)
Gan Z, He J, Jin Q, Ma Q, Wang C, Zhong X.   +5 more
europepmc   +1 more source

The Ganoderma atrum Polysaccharide PSG-1 Attenuates Acrylamide-Induced Hepatotoxicity by Modulating the FXR-FGF15-Mediated Gut-Liver Axis. [PDF]

Mol Nutr Food Res
Chen S, Nie C, Wang Y, Guo Z, Zhao K, Yu Q, Xie J, Chen Y.   +7 more
europepmc   +1 more source

Mangiferin alleviates metabolic-associated fatty liver disease by modulating gut microbiota and FXR signaling pathway to regulate bile acid metabolism. [PDF]

Front Pharmacol
Zheng L, Xie Q, Yao S, Chen M, Zhao W, Li R, Cheng J, Zhang Y.   +7 more
europepmc   +1 more source

GV-971 remodels the gut microbiota-bile acid-FXR axis to ameliorate obesity and metabolic dysfunction. [PDF]

Cell Discov
Zhang N, Ye X, Wang K, Hu Y, Wang Z, Huang L, Chen X, Yan D, Fu W, Xue Q, Sun S, Xu Y, Tang D, Chen X, Zhou L, Liu J.   +15 more
europepmc   +1 more source

Hyodeoxycholic acid ameliorates tacrolimus-induced diabetes by modulating the FXR-FGF15 axis. [PDF]

Front Pharmacol
Hu N, Qian M, Liu Y, Jiang Z, Xu C, Zhang W, Jiang J.   +6 more
europepmc   +1 more source

FXR Regulates Intestinal Cancer Stem Cell Proliferation [PDF]

Cell, 2019
Increased levels of intestinal bile acids (BAs) are a risk factor for colorectal cancer (CRC). Here, we show that the convergence of dietary factors (high-fat diet) and dysregulated WNT signaling (APC mutation) alters BA profiles to drive malignant ...
Eiji Yoshihara, Rob Knight, Qiyun Zhu
exaly   +3 more sources