Results 51 to 60 of about 5,954 (200)

Mechanisms of regulation and diversification of deubiquitylating enzyme function [PDF]

, 2017
Deubiquitinating enzymes (DUBs) are proteases that reverse protein ubiquitylation and therefore modulate the outcome of this posttranslational modification.
Abdul Rehman, Akhavantabasi, Atanassov, Baker, Bingol, Borodovsky, Clague, Clague, Cohn, Coornaert, Cotto-Rios, Deng, Dufner, Eguether, Elliott, Elliott, Faronato, Feng, Floor, García-Santisteban, Gomez-Ferreria, Hassink, Heideker, Herhaus, Heride, Huang, Huang, Huang, Hutti, Jahan, Jongsma, Joo, Juang, Kayagaki, Kedersha, Kee, Kee, Kim, Kobayashi, Köhler, Koutelou, Kulathu, Kupka, Lee, Lee, Lee, Lee, Legarda, Li, Liang, Lin, Liu, Liu, Long, Lund, Ma, Mashtalir, Meulmeester, Millard, Mizuno, Naik, Nakada, Nakagawa, Nakamura, Nijman, Nijman, O'Donnell, Pahl, Perrody, Piatkov, Qiu, Redman, Reincke, Sahtoe, Samara, Scaglione, Schaeffer, Schlicher, Seki, Shao, Sims, Smogorzewska, Soares, Soncini, Sowa, Sun, Sun, Takiuchi, Tasaki, Thorne, Todi, Udeshi, Urbe, VanderLinden, Vugmeyster, Wagner, Wang, Wertz, Wertz, Wiborg, Wiener, Wijnhoven, Worden, Xu, Xu, Yan, Yang, Yang, Yang, Yao, Yao, Ye, Zeqiraj, Zhang, Zheng   +114 more
core   +3 more sources

Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH

Open Biology, 2023
G3BP is the central node within stress-induced protein–RNA interaction networks known as stress granules (SGs). The SG-associated proteins Caprin-1 and USP10 bind mutually exclusively to the NTF2 domain of G3BP1, promoting and inhibiting SG formation ...
Tim Schulte, Marc D. Panas, Xiao Han, Lucy Williams, Nancy Kedersha, Jonas Simon Fleck, Timothy J. C. Tan, Xaquin Castro Dopico, Anders Olsson, Ainhoa Moliner Morro, Leo Hanke, Johan Nilvebrant, Kim Anh Giang, Per-Åke Nygren, Paul Anderson, Adnane Achour, Gerald M. McInerney   +16 more
doaj   +1 more source

RNA granules: the good, the bad and the ugly [PDF]

, 2011
Processing bodies (PBs) and Stress Granules (SGs) are the founding members of a new class of RNA granules, known as mRNA silencing foci, as they harbour transcripts circumstantially excluded from the translationally active pool.
Boccaccio, Graciela Lidia, Desbats, Maria Andrea, Loschi, Mariela, Thomas, Maria Gabriela   +3 more
core   +2 more sources

Urinary galectin-3 binding protein (G3BP) as a biomarker for disease activity and renal pathology characteristics in lupus nephritis

Arthritis Research & Therapy, 2022
Objective There is an urgent need to identify novel biomarkers of LN to reflect renal histological changes. This study aims to investigate urinary G3BP levels in LN patients and their association with renal disease activity both clinically and ...
Huihua Ding, Yiwei Shen, Cheng Lin, Ling Qin, Shijun He, Min Dai, Shinji L. Okitsu, Julie A. DeMartino, Qiang Guo, Nan Shen   +9 more
doaj   +1 more source

Galectin-3-binding protein : a serological and histological assessment in accordance with hepatitis C-related liver fibrosis [PDF]

, 2010
A
Cheung, Kin Jip, Colle, Isabelle, Deforce, Dieter, Libbrecht, Louis, Tilleman, Kelly, Van Vlierberghe, Hans   +5 more
core   +2 more sources

Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen [PDF]

, 2017
Re-emergence of chikungunya virus, a mosquito-transmitted pathogen, is of serious public health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the virus has caused major epidemic outbreaks in Africa, Asia, the Indian ...
Burt, Felicity J, Chen, Weiqiang, Herrero, Lara J, Kohl, Alain, Lenschow, Deborah J, Mahalingam, Suresh, Merits, Andres, Miner, Jonathan J, Ng, Lisa FP, Rudd, Penny A, Schnettler, Esther, Taylor, Adam, Zaid, Ali   +12 more
core   +1 more source

Contrasting Pathology of the Stress Granule Proteins TIA-1 and G3BP in Tauopathies [PDF]

Journal of Neuroscience, 2012
Stress induces aggregation of RNA-binding proteins to form inclusions, termed stress granules (SGs). Recent evidence suggests that SG proteins also colocalize with neuropathological structures, but whether this occurs in Alzheimer's disease is unknown.
Tara, Vanderweyde, Haung, Yu, Megan, Varnum, Liqun, Liu-Yesucevitz, Allison, Citro, Tsuneya, Ikezu, Karen, Duff, Benjamin, Wolozin   +7 more
openaire   +2 more sources

Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics [PDF]

, 2017
Liquid-liquid phase separation (LLPS) of RNA-binding proteins plays an important role in the formation of multiple membrane-less organelles involved in RNA metabolism, including stress granules.
Abigail M. Janke, Aguzzi, Albert Konijnenberg, Alex Volkov, Altmeyer, Andersen, Ash, Aumiller, Boeynaems, Boeynaems, Brangwynne, Brangwynne, Brangwynne, Burke, Castello, Ciryam, Conicella, Cox, Cox, David, DeJesus-Hernandez, Denes Kovacs, Dirk Daelemans, Dormann, Edbauer, Elke Bogaert, Emara, Evy Timmerman, Figley, Francis Impens, Frank Sobott, Frederic Rousseau, Freibaum, Frey, Hawe, Hennig, J. Paul Taylor, Jain, Joost Schymkowitz, Jovičić, Kato, Kedersha, Kedersha, Kedersha, Kim, King, Kwon, Lee, Lin, Lin, Liu, Lopez-Gonzalez, Ludo Van Den Bosch, Mainak Guharoy, March, Mathias De Decker, Mitrea, Mizielinska, Molliex, Mori, Murakami, Nancy Kedersha, Nicolas L. Fawzi, Nott, Olzscha, Patel, Paul Anderson, Peter Tompa, Philip Van Damme, Pieter Baatsen, Ramaswami, Regina-Maria Kolaitis, Renton, Renton, Schwartz, Steven Boeynaems, Tao, Thandapani, Thomas Vercruysse, Tiraferri, Tom Jaspers, Tompa, Tompa, Topisirovic, Varadi, Veronica H. Ryan, Wen, Wheeler, Wim Robberecht, Yamakawa, Zhang   +90 more
core   +4 more sources

FUS mutant human motoneurons display altered transcriptome and microRNA pathways with implications for ALS pathogenesis [PDF]

, 2017
The FUS gene has been linked to amyotrophic lateral sclerosis (ALS). FUS is a ubiquitous RNA-binding protein, and the mechanisms leading to selective motoneuron loss downstream of ALS-linked mutations are largely unknown.
Alfano, Vincenzo, Bozzoni, Irene, Colantoni, Alessio, DE SANTIS, Riccardo, DE TURRIS, Valeria, Peruzzi, Giovanna, Rosa, Alessandro, Santini, Laura   +7 more
core   +2 more sources

The Network of Interactions between the Porcine Epidemic Diarrhea Virus Nucleocapsid and Host Cellular Proteins

Viruses, 2022
Host–virus protein interactions are critical for intracellular viral propagation. Understanding the interactions between cellular and viral proteins may help us develop new antiviral strategies.
Jianwei Zhou, Yonghui Qiu, Jie Zhao, Yongxia Wang, Ning Zhu, Dedong Wang, Yongqiu Cui, Jinshuo Guo, Tong Sun, Ying Ji, Zhi Wu, Penghui Zeng, Jingyi Li, Xufei Feng, Lei Hou, Jue Liu   +15 more
doaj   +1 more source