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Getah Virus in Review: An Emerging Zoonotic Arbovirus
Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.Getah virus (GETV), a zoonotic virus, belongs to Togaviridae, Alphavirus. GETV leads to diarrhea in piglets and dysfunction of the reproductive system in sows, with pregnant sows potentially experiencing abortion, fetal death, or weak offspring, causing a severe impact on the livestock industry and resulting in economic losses.
Zhengyi Qiu +7 more
wiley +1 more source
Journal of Virology, 2020 Old World alphaviruses comprise several medically relevant viruses, including chikungunya virus and Ross River virus. Recurrent outbreaks and the lack of antivirals and vaccines demand ongoing research to fight the emergence of these infectious diseases. In this context, a thorough investigation of virus-host interactions is critical.
Benjamin Götte +4 more
openaire +3 more sources
Prediction of acute multiple sclerosis relapses by transcription levels of peripheral blood cells [PDF]
, 2009 Background The ability to predict the spatial frequency of relapses in multiple sclerosis (MS) would enable physicians to decide when to intervene more aggressively and to plan clinical trials more accurately.
Michael Gurevich +59 more
core +2 more sources
Advanced Science, Volume 12, Issue 48, December 29, 2025.Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon +8 more
wiley +1 more source
Analyzing plant stress granules in response to plant viruses [PDF]
, 2018 Plant viruses have the ability to redirect host machineries and processes to establish a productive infection. Virus-host interactions lead to the reprogramming of the plant cell cycle and transcriptional controls, inhibition of cell death pathways ...
Krenz, Björn
core
Novel Staufen1 ribonucleoproteins prevent formation of stress granules but favour encapsidation of HIV-1 genomic RNA [PDF]
, 2010 Human immunodeficiency virus type 1 (HIV-1) Gag selects for and mediates genomic RNA (vRNA) encapsidation into progeny virus particles. The host protein, Staufen1 interacts directly with Gag and is found in ribonucleoprotein (RNP) complexes containing ...
Abrahamyan, Levon G. +11 more
core +2 more sources
The FEBS Journal, Volume 292, Issue 23, Page 6365-6399, December 2025.GLE1 plays a direct role mRNA regulation, translation, and formation of cytosolic stress granules. GLE1 dysfunction has been associated with devastating diseases, including lethal congenital contracture syndrome 1(LCCS1), a rare disorder enriched in isolated populations.
Tomáš Zárybnický +22 more
wiley +1 more source
Molecular Therapy: Methods & Clinical Development, 2014 Vectors based on recombinant adeno-associated viruses (rAAV) attract a growing interest for human gene therapy. Recently, it was shown that many rAAV serotypes produced by transient transfection of human embryonic kidney 293 cell line (HEK293) are ...
Jerome Denard +4 more
doaj +1 more source
Frontiers in Genetics, 2021 Background: Diabetic retinopathy (DR) is the most important manifestation of diabetic microangiopathy. MicroRNAs (miRNAs), members of non-coding RNAs, have been frequently reported to regulate various diseases including DR.
Haijun Zhao, Yanhui He
doaj +1 more source
Influenza A Virus Host Shutoff Disables Antiviral Stress-Induced Translation Arrest [PDF]
, 2014 Influenza A virus (IAV) polymerase complexes function in the nucleus of infected cells, generating mRNAs that bear 5′ caps and poly(A) tails, and which are exported to the cytoplasm and translated by host machinery.
Anderson, Paul +5 more
core +1 more source