Results 81 to 90 of about 1,908 (177)

FGFR2 Fusions or Rearrangements in Young Intrahepatic and Perihilar Cholangiocarcinoma Patients: Key Genetic Insights From a Pan‐Asian Study

Hepatology Research, Volume 56, Issue 1, Page 78-88, January 2026.
FGFR2 Alterations in Young Adults with cholangiocarcinoma was common. Intrahepatic cholangiocarcinoma (ICC) is a rare liver cancer, typically seen in older adults. This study focused on younger patients across Asia, examining changes in the FGFR2 gene that may drive cancer growth.
Yuta Maruki, Yasushi Yatabe, Chiharu Mizoguchi, Kathleen Yasmin de Almeida, Aumkhae Sookprasert, Charuwan Akewanlop, Ming‐Huang Chen, Ekaphop Sirachainan, Dao Van Tu, Rozita Abdul Malik, Chaiyut Charoentum, Hwoei Fen Soo Hoo, Suhana Yusak, Tsung‐Hao Liu, Rangasamy Ramachandran, Patrapim Sunpaweravong, Pei Jye Voon, Najihah Abu Bakar, Junki Mizusawa, Hitomi Sumiyoshi Okuma, Kenichi Nakamura, Chigusa Morizane, Takuji Okusaka   +22 more
wiley   +1 more source

FMDV leader protease cleaves G3BP1 and G3BP2 and inhibits stress granule formation

Journal of Virology, 2019
Like other viruses, the picornavirus foot-and-mouth disease virus (FMDV, genus aphthovirus), one of the most notorious pathogens in global livestock industry, needs to navigate antivirals host responses to establish an infection. There is substantial insight into how FMDV suppresses the type I IFN response, but it is largely unknown whether and how ...
Visser, Linda J, Medina, Gisselle N, Rabouw, Huib H, de Groot, Raoul J, Langereis, Martijn A, de Los Santos, Teresa, van Kuppeveld, Frank J M   +6 more
openaire   +2 more sources

Supplementary Figure S3 from Association of USP10 with G3BP2 Inhibits p53 Signaling and Contributes to Poor Outcome in Prostate Cancer

, 2018
Supplementary Figure S3. USP10-mediated oncogenic function is observed in cell with high G3BP2 expression.
Satoru Takahashi (32871), Satoshi Inoue (221875), Tetsuya Fujimura (818629), Ken-ichi Takayama (482421), Takashi Suzuki (8491)   +4 more
core   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, Volume 9, Issue 12, December 2025.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source

Data from Association of USP10 with G3BP2 Inhibits p53 Signaling and Contributes to Poor Outcome in Prostate Cancer

, 2023
<div>Abstract<p>Ubiquitin-specific protease 10 (USP10) is known to deubiquitylate its target proteins, mainly to enhance their stabilities. USP10 maintains p53 protein levels and controls epigenetic changes induced by the androgen receptor (AR).
Satoshi Inoue, Satoru Takahashi, Tetsuya Fujimura, Takashi Suzuki, Ken-ichi Takayama   +4 more
openaire   +1 more source

Down-regulation of miR-515-5p contributes to the development of rhabdomyosarcoma through G3BP2

, 2018
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma found in children and young adults. By screening for potential tumor suppressive microRNAs in two RMS cell lines, we found that miR-515-5p exibited tumor suppressive functions: it is ...
Han, Lifang
core  

G3BP2 is necessary for corticosterone-induced autophagic cell death in adult hippocampal neural stem cells

Autophagic cell death (ACD);Corticosterone (CORT);Hippocampal neural stem (HCN);G3BP1;G3BP2;Stress ...
Juhyun Jung
core   +1 more source

Supplementary Figure S5 from Association of USP10 with G3BP2 Inhibits p53 Signaling and Contributes to Poor Outcome in Prostate Cancer

, 2018
Supplementary Figure S5. High expression of G3BP2 is a prognostic factor of prostate cancer patients.
Satoru Takahashi (32871), Satoshi Inoue (221875), Tetsuya Fujimura (818629), Ken-ichi Takayama (482421), Takashi Suzuki (8491)   +4 more
core   +1 more source

Correction to: Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis

Molecular Cancer, 2020
An amendment to this paper has been published and can be accessed via the original article.
Hongwei Liu, Junming Bi, Wei Dong, Meihua Yang, Juanyi Shi, Ning Jiang, Tianxin Lin, Jian Huang   +7 more
doaj   +1 more source

CircLRBA Promotes Epithelial‐Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1

Advanced Science, Volume 12, Issue 48, December 29, 2025.
CircLRBA is highly expressed in breast cancer (BC) and associated with poor overall survival. Zeb1 mediated circLRBA facilitates BC cell proliferation, invasion, docetaxel (DTX) resistance and inhibits the infiltration of CD8+ T cell. CircLRBA could combine with SPOP to suppress the Twist1 ubiquitination degradation and enhances PD‐L1 transcription ...
Xiaosong Wang, Xin Yang, Lei Xing, Hang Chen, Fuming Xie, Bin Wang, Bowen Shi, Yan Yang, Junxia Chen   +8 more
wiley   +1 more source