Results 1 to 10 of about 60,324 (289)

Comparison effects of pre-emptive gabapentin and meloxicam for postoperative pain in white new zealand rabbits undergoing ovariohysterectomy using the grimace scale [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2023
The study aimed to evaluate the effectiveness of Gabapentin in controlling postoperative pain in New Zealand white rabbits after ovariohysterectomy.
Hourieh MARGHOUB   +2 more
doaj   +1 more source

Development of a novel niosomal formulation for Gabapentin [PDF]

open access: yesIranian Journal of Colorectal Research, 2021
Background: Gabapentin is an anticonvulsant drug prescribed to treat partial seizures and neuropathic pain. Nisomes as a type of lipid based drug carriers can improve the pharmacokinetic properties of therapeutic agents.
Iman Akbarzadeh   +3 more
doaj   +1 more source

Gabapentin [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1996
ABSTRACT:Gabapentin is a novel antiepileptic drug that has recently been introduced in Canada. Although its mechanism of action remains to be defined gabapentin is effective in a number of seizure models which predict its efficacy in partial and tonic-clonic seizures. Clinical studies support the clinical efficacy of gabapentin as adjunctive therapy in
  +6 more sources

Prenatal Exposure to Gabapentin Alters the Development of Ventral Midbrain Dopaminergic Neurons

open access: yesFrontiers in Pharmacology, 2022
Background: Gabapentin is widely prescribed as an off-label drug for the treatment of various diseases, including drug and alcohol addiction. Approximately 83–95% of the usage of gabapentin is off-label, accounting for more than 90% of its sales in the ...
Walaa F. Alsanie   +25 more
doaj   +1 more source

Gabapentin [PDF]

open access: yesEpilepsia, 1999
Summary:Gabapentin (GBP) is a antiepileptic drug (AED) indicated as adjunct therapy for treatment of partial seizures, with and without secondary generalization, in patients 12 and older with epilepsy. GBP (1‐(aminomethyl) cyclohexaneacetic acid) is structurally related to γ‐aminobutyric acid (GABA), which readily crosses the blood‐brain barrier ...
  +5 more sources

The Effect of Gabapentin Plus Celecoxib on Pain and Associated Complications After Laminectomy [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Prevention and treatment of postoperative pain is a major challenge in postoperative care and well-being of the surgical patient. The multimodal analgesic method has been recommended as an alternative treatment for the management of ...
Aminolah Vasigh   +3 more
doaj   +1 more source

Perbandingan Tiga Dosis Gabapentin Oral terhadap Nyeri Pascabedah, Sedasi, dan Mual-Muntah pada Histerektomi Total dengan Anestesi Spinal

open access: yesJurnal Anestesi Obstetri Indonesia, 2021
Latar Belakang: Gabapentin dapat mencegah nyeri nosiseptif, nyeri neuropatik, inflamasi akut dan mengurangi nyeri pasca operasi. Tujuan: penelitian ini membandingkan tiga dosis gabapentin oral pada operasi histerektomi total dengan anestesi spinal ...
Rakhmat Ilhamsyah   +3 more
doaj   +1 more source

Plasma disposition of gabapentin after the intragastric administration of escalating doses to adult horses

open access: yesJournal of Veterinary Internal Medicine, 2020
Background In humans, gabapentin an analgesic, undergoes non‐proportional pharmacokinetics which can alter efficacy. No information exists on the pharmacokinetics of dosages >20 mg/kg, escalating dosages or dose proportionality of gabapentin in horses ...
Jenifer R. Gold   +4 more
doaj   +1 more source

Assessment of the role of gabapentin in patients with supratentorial tumours undergoing craniotomy under general anaesthesia: A double-blind randomised study

open access: yesJournal of Neuroanaesthesiology and Critical Care, 2017
Background: Gabapentin attenuates the haemodynamics, decreases the catecholamine release and has a neuroprotective effect. The aim of the present study was to assess the effect of gabapentin in patients with supratentorial brain tumours undergoing ...
Rabie Soliman, Gomaa Zohry
doaj   +3 more sources

The Effect of Once-Daily Gabapentin Extended Release Formulation in Patients With Postamputation Pain

open access: yesFrontiers in Pharmacology, 2019
ObjectivesTo compare gabapentin extended-release, a gastro-retentive formulation, in relieving postamputation pain among gabapentin-experienced and gabapentin-naïve patients.DesignOpen-labeled pilot study.SubjectsSixteen patients with postamputation pain
Nebojsa Nick Knezevic   +9 more
doaj   +1 more source

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