Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Ibrain, EarlyView., 2023 This study compared the clinical effectiveness and treatment satisfaction of Pregabalin and Gabapentin triple therapy for neuropathic pain in a real‐world setting. The primary outcome measured the reduction in mean Self‐Administered Leeds Assessment of Neuropathic Symptoms and Signs pain score value from baseline to 12 weeks posttreatment.
Nithya Raju +7 more
wiley +1 more source
Global Medical & Health Communication, 2020 Diabetic neuropathy is the most common microvascular complication of diabetes mellitus (DM) occurring in 60–70% of the world's DM population, 40% of the DM population in Asia, and 41% of the DM population in Indonesia.
Mochamad Firdaus Bhuanaputra +2 more
doaj +1 more source
Effect of pretreatment with gabapentin on withdrawal movement associated with intravenous rocuronium injection [PDF]
Korean Journal of Anesthesiology, 2011 BackgroundThe major disadvantage of rocuronium is the withdrawal movement associated with its injection. The analgesic effect of perioperative gabapentin has been evaluated.
Jin Sun Yoon +6 more
doaj +1 more source
Effects of pregabalin and gabapentin on postoperative pain and opioid consumption after laparoscopic cholecystectomy [PDF]
Korean Journal of Anesthesiology, 2017 BackgroundGabapentin and pregabalin are antiepileptic drugs that are also used for chronic pain treatment. This study evaluated the effects of pregabalin and gabapentin on postoperative pain in patients undergoing laparoscopic cholecystectomy.MethodsA ...
Mohammad Eidy +5 more
doaj +1 more source
The effects of gabapentin pretreatment on brain injury induced by focal cerebral ischemia/reperfusion in the rat [PDF]
Korean Journal of Anesthesiology, 2010 BackgroundExperimental studies have shown that gabapentin can reduce neuronal injury in the setting of cerebral ischemia, but the mechanisms have not yet been clearly determined.
Yoo-kyung Kim +4 more
doaj +1 more source
Pregabalin: a range of misuse-related unanswered questions [PDF]
, 2019 © 2019 The Authors.
Chiappini, Stephania, Schifano, Fabrizio
core +2 more sources
Treatments for spasticity and pain in multiple sclerosis: a systematic review [PDF]
, 2003 Objectives: To identify the drug treatments currently available for the management of spasticity and pain in multiple sclerosis (MS), and to evaluate their clinical and cost-effectiveness.
Beard, S.M., Hunn, A., Wight, J.
core +1 more source
Botulinum toxin for the treatment of lower limb cramp pain in patients with Amyotrophic Lateral Sclerosis [PDF]
, 2020 Background: Muscle cramps and pain associated with them can be seen in patients with amyotrophic lateral sclerosis (ALS) and are known to reduce the quality of life. Pharmacological treatment may not benefit all patients in treating these cramps.
Govindarajan, Raghav +2 more
core +2 more sources
Pharmacokinetics and pharmacodynamics of repeat dosing of gabapentin in adult horses
Journal of Veterinary Internal Medicine, 2022 Background The repeated administration of high doses of gabapentin may provide better analgesia in horses than current clinical protocols. Hypothesis and Objectives Administration of gabapentin at 40 and 120 mg/kg PO q 12 h for 14 days will not alter ...
Jenifer R. Gold +4 more
doaj +1 more source