Results 41 to 50 of about 60,324 (289)
Pain relief by supraspinal gabapentin requires descending noradrenergic inhibitory controls
PAIN Reports, 2018 . Introduction:. Gabapentin regulates pain processing by direct action on primary afferent nociceptors and dorsal horn nociresponsive neurons. Through an action at supraspinal levels, gabapentin also engages descending noradrenergic inhibitory controls ...
Dina L. Juarez-Salinas +3 more
doaj +1 more source
Comparison of gabapentin and ketotifen in treatment of uremic pruritus in hemodialysis patients [PDF]
, 2016 Objectives: Uremic pruritus is a common problem in hemodialysis patients. Several treatments have been used for decreasing itching in these patients. Gabapentin and ketotifen are two drugs used for treating uremic patients.The aim of this study was to ...
Amirkhanlou, S. +4 more
core +1 more source
Successful medical management of an epidural abscess in a dog [PDF]
, 2017 A seven-month-old entire male dobermann presented with acute onset neck pain and left thoracic limb lameness. The dog had a similar episode eight weeks before presentation that responded to meloxicam.
Durand, Alexane +3 more
core +1 more source
Gabapentin Extended-Release ??? Depomed
Drugs in R & D, 2007 Depomed is developing an extended-release (ER) oral formulation of gabapentin, a GABA receptor agonist commonly used for the treatment of epilepsy and seizures, neuropathic pain and hot flushes. Gabapentin ER is based on the company's proprietary AcuForm drug delivery technology, which is part of the Gastric Retention (GR) family of technologies; this ...
openaire +2 more sources
Advanced Science, EarlyView.This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia +6 more
wiley +1 more source
Journal of Pain Research, 2023 Jufriady Ismy,1 Dessy R Emril,2 Said Alfin Khalilullah,1 Muhammad Puteh Mauny1 1Department of Urology, Faculty of Medicine, Universitas Syiah Kuala/Dr.
Ismy J +3 more
doaj
Evaluation of behavior in transgenic mouse models to understand human congenital pain conditions [PDF]
, 2018 BACKGROUND: Containing a brain for signal processing and decision making, and a peripheral component for sensation and response, the nervous system provides higher organisms a powerful method of interacting with their environment.
Bullock, Daniel
core
Annals of Neurology, EarlyView.Objective Antiseizure medication (ASM) use during pregnancy has increased over the past decade. However, evidence linking prenatal ASM exposure to neurodevelopmental disorders (NDDs) in offspring remains inconsistent. This study evaluated whether prenatal ASM exposure increases the risk of NDDs in children.
Odile Sheehy +13 more
wiley +1 more source
Review of the Treatment of Restless Legs Syndrome: Focus on Gabapentin Enacarbil
Journal of Central Nervous System Disease, 2012 The FDA approved gabapentin enacarbil in 2011 as the first non-dopaminergic agent for the treatment of restless legs syndrome (RLS) symptoms. Although gabapentin enacarbil is a pro-drug of gabapentin, its pharmacokinetics differ. Absorption of gabapentin
Rachel A. Burke, Michele A. Faulkner
doaj +1 more source
Teratogenic effects of gabapentin on the skeletal system of Balb/C mice fetuses [PDF]
, 2009 Objectives: To evaluate the effects of gabapentin )GBP( administration on mice fetuses. Methods: This study was carried out in Birjand University of Medical Sciences during 2008.
Afshar, M. +4 more
core