Results 51 to 60 of about 60,324 (289)

Renal impairment as a possible side effect of gabapentin - A single case report [PDF]

, 1998
A bipolar I manic patient was treated successfully by adding gabapentin to perazine and clonazepam. Also initially tolerated well, an increase of creatinine after several weeks of GP (2000 mg) was observed which was reversible after discontinuation of GP.
Bungert, Martina, Dittert, Sebastian, Erfurth, Andreas, Grunze, Heinz   +3 more
core   +1 more source

Sleep Dysfunction in Fibromyalgia and Therapeutic Approach Options [PDF]

, 2020
Fibromyalgia, characterised by persistent pain, sleep disturbance, fatigue and cognitive dysfunction, is a central sensitivity syndrome that also involves abnormality in peripheral generators and in the hypothalamic pituitary adrenal axis.
Lawson, Kim
core   +1 more source

Safety and pharmacokinetics of a novel potent GABA analogue crisugabalin in Chinese subjects with various degrees of renal impairment

British Journal of Clinical Pharmacology, EarlyView.
Aims Crisugabalin is a novel calcium channel α2δ subunit ligand and a highly selective oral gamma‐aminobutyric acid (GABA) analogue developed for the treatment of diabetic peripheral neuropathic pain (DPNP) and postherpetic neuralgia (PHN). This study investigated pharmacokinetic properties and safety of crisugabalin in subjects with renal impairment ...
Shibeilei Lin, Ye Wang, Chao Hu, Yanhuan Feng, Xi Tang, Ping Fu, Jia Miao   +6 more
wiley   +1 more source

GABAB Receptors Do Not Mediate the Inhibitory Actions of Gabapentin on the Spinal Reflex in Rats

Journal of Pharmacological Sciences, 2004
The clinical effectiveness of gabapentin for the treatment of epilepsy, spasticity, and neuropathic pain has been established. The mechanisms responsible for those actions, however, are still not clearly understood.
Shinobu Shimizu, Motoko Honda, Mitsuo Tanabe, Hideki Ono   +3 more
doaj   +1 more source

Trends in long-term prescribing of dependence forming medicines [PDF]

, 2019
Using patient-level primary care data to estimate the extent to which antidepressant medicines are prescribed to people continuously for long periods of time.
McManus, S., Nguyen, A., Sehmi, R., Smith, N.   +3 more
core  

Emerging pharmacotherapy of tinnitus [PDF]

, 2009
Tinnitus, the perception of sound in the absence of an auditory stimulus, is perceived by about 1 in 10 adults, and for at least 1 in 100, tinnitus severely affects their quality of life.
Ana Belén Elgoyhen, Azevedo AA, Bahmad FM, Berthold Langguth, Busto U, Courtney KR, Domeisen H, Feder R, Gananca MM, Goebel G, Goodnick PJ, Gresser U, Guitton MJ, Guitton MJ, Hastak SM, Henry JA, Hilton M, Holstein N, House JW, Kuchar DL, Langguth B, Lenarz T, Mahadevan S, Mardini MK, McCabe BF, Melcher JR, Moller AR, Moller AR, Newman CW, Oliver D, Podoshin L, Richard Salvi, Rogawski MA, Roth SH, Schlee W, Shambaugh GE, Shea JJ, Shulman A, Sieghart W, Tandon R, Wei BPC, Williams SH, Willow M, Zapp JJ   +43 more
core   +1 more source

Drug poisonings following bariatric surgery: Case series report

British Journal of Clinical Pharmacology, EarlyView.
Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari, Fannie LaJeunesse‐Trempe, Stephen Morley, Caroline Copeland   +3 more
wiley   +1 more source

William H. Sorrell, Attorney General of Vermont, et al. v. IMS Health Inc., et al. - Amicus Brief in Support of Petitioners [PDF]

, 2011
On April 26, 2011, the US Supreme Court will hear oral arguments in the Vermont data mining case, Sorrell v. IMS Health Inc. Respondents claim this is the most important commercial speech case in a decade. Petitioner (the State of Vermont) argues this is
Orentlicher, David, Outterson, Kevin, Pasquale, Frank A, Robertson, Christopher T.   +3 more
core   +2 more sources

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

Uremic pruritus in hemodialysis patients: treatment with desloratidine versus gabapentin

Brazilian Journal of Nephrology, 2012
INTRODUCTION: Uremic pruritus is common among dialysis patients. Effective treatments are not readily available. Early evidence with antihistamines and gabapentin indicate variable effects.
Diego Marquez, Carolina Ramonda, Jorge E. Lauxmann, Cesar A. Romero, Valeria L. Vukelic, Carolina Martinatto, Belén Barrón, Pablo A. Novoa, Aldo J. Peixoto, Marcelo Orías   +9 more
doaj   +1 more source