Results 91 to 100 of about 3,167 (176)
GABARAPL1 expression within the diencephalon.
, 2013 Immunohistochemical analysis of WT mouse brain tissue with an anti-GABARAPL1 antibody. Images represent typical GABARAPL1 protein expression patterns in neurons found in the anterodorsal nucleus of the thalamus-AD (b) and paraventricular nucleus of the ...
Jianhua Zhang (6347) +7 more
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The Journal of Poultry Science, 2018 Autophagy, an intracellular bulk protein degradation system in skeletal muscle, is increased under catabolic conditions resulting in muscle atrophy. This study aimed to investigate the effects of insulin, insulin-like growth factor (IGF)-I, and amino ...
Kazuki Nakashima, Aiko Ishida
doaj +1 more source
GABARAPL1 expression in embryonic cortical primary cultures grown in NBM or DMEM medium.
, 2013 Immunostaining using anti-GFAP (green), anti-GABARAPL1 (green) or anti-NeuN (red) of embryonic cortical primary neurons grown in NBM or Dulbecco's Modified Eagle Medium (DMEM) supplemented with 10% FBS.
Jianhua Zhang (6347) +7 more
core +1 more source
vIRF-1 binds directly to GABARAPL1 in an LIR-independent manner.
, 2023 (A) Schematic structure of vIRF-1:PD, Proline-rich domain; DBD, DNA-binding domain; and IAD, IRF-association domain. LC3-interacting regions (LIRs) were searched for using a position-specific scoring matrix (PSSM) via the web-based software iLIR, and a ...
Chang-Yong Choi (3597962) +2 more
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Oncotarget, 2017 The GABARAPL1 protein belongs to the ATG8 family whose members are involved in autophagy. Our laboratory previously demonstrated that GABARAPL1 associates with autophagic vesicles, regulates autophagic flux and acts as a tumor suppressor protein in breast cancer.
Poillet-Perez, Laura +11 more
openaire +5 more sources
Glycophagy is involved in cardiac glycogen regulation in response to exercise
Current Research in PhysiologyCardiac glycogen-autophagy (‘glycophagy’) is disturbed in cardiometabolic pathologies. The physiological role of cardiac glycophagy is unclear. Exercise induces transient cardiac glycogen accumulation.
Samuel L. James +7 more
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Analysis of novel therapeutic targets and construction of a prognostic model for hepatocellular carcinoma [PDF]
PeerJBackground The prognosis of patients with hepatocellular carcinoma (HCC) remains suboptimal due to limited biomarkers. Although ferroptosis and cuproptosis have emerged as promising therapeutic targets, their prognostic significance in HCC remains ...
Pengyuan Lei +5 more
doaj +2 more sources
ZNF197-AS1/miR-425/GABARAPL1 axis: a novel regulatory mechanism in uveal melanoma
American Journal of Physiology-Cell PhysiologyThis study identifies the ZNF197-AS1/miR-425/GABARAPL1 axis as a novel regulatory mechanism in uveal melanoma. ZNF197-AS1 upregulates GABARAPL1 by sponging miR-425, inhibiting UM cell proliferation, migration, and invasion. This discovery highlights a potential therapeutic target, providing new insights into UM progression and patient outcomes.
Chao Zhang, Shuai Wu
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Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization
Scientific Reports, 2017 HIV-1 Nef is an important pathogenic factor for HIV/AIDS pathogenesis. Studies have shown that the association of Nef with the inner leaflet of the plasma membrane and with endocytic and perinuclear vesicles is essential for most activities of Nef. Using
Alexandra Boeske +8 more
doaj +1 more source
GABARAPL1 expression within the mesencephalon.
, 2013 Immunohistochemical analysis of WT mouse brain tissue with an anti-GABARAPL1 antibody. Displayed are representative images of the ventral tegmental area (VTA) (b), the substantia nigra pars compacta (SNpc) (c), and hippocampal formation (HPF) (d).
Jianhua Zhang (6347) +7 more
core +1 more source