GABARAPL1 is differentially expressed in the brains of patients with psychotic disorders.
, 2020 We used public and published microarray data (1, 2) to identify the most significant gene expression changes in the brains of patients with psychotic disorders.
Shahan Mamoor
core +3 more sources
Identification of mitophagy-related genes in patients with acute myocardial infarction [PDF]
HereditasMitophagy is involved in acute myocardial infarction (AMI) process. However, the role of mitophagy-related genes (MRGs) in the AMI process is not well illustrated. We identified MRGs involved in AMI by bioinformatics analysis.
Ju-Ying Li +7 more
doaj +2 more sources
Cells, 2022 Vaccine therapy is a promising method of research to promote T cell immune response and to develop novel antitumor immunotherapy protocols. Accumulating evidence has shown that autophagy is involved in antigen processing and presentation to T cells.
Leïla Fonderflick +5 more
doaj +3 more sources
Identification of autophagy-related genes in intestinal ischemia-reperfusion injury and their role in immune infiltration [PDF]
Frontiers in PhysiologyBackgroundIntestinal ischemia-reperfusion (II/R) injury is a serious condition characterized by high morbidity and mortality rates. Research has shown that II/R injury is closely linked to autophagy and immune dysregulation.
Yichen Hu +8 more
doaj +2 more sources
GABARAP proteins regulate the packaging of HIV-1 genomic RNA into virions [PDF]
EMBO ReportsIn addition to their role in canonical autophagy, autophagy proteins (ATG) contribute to various cellular processes, including phagocytosis, membrane remodeling, and vesicle secretion.
Marjory Palaric +9 more
doaj +2 more sources
Rapid induction of p62 and GABARAPL1 upon proteasome inhibition promotes survival before autophagy activation [PDF]
Journal of Cell Biology, 2018 Proteasome inhibitors are used as research tools and to treat multiple myeloma, and proteasome activity is diminished in several neurodegenerative diseases. We therefore studied how cells compensate for proteasome inhibition. In 4 h, proteasome inhibitor
Alfred Goldberg +3 more
core +3 more sources
Role of Autophagy in Goose Astrovirus-Induced Renal Injury in Goslings [PDF]
AnimalsGoose astrovirus (GoAstV) is a newly identified virus affecting geese, leading to goose gout, which is marked by urate deposits in organs and joints. This research investigates the role of autophagy in renal damage caused by GoAstV in goslings.
Jun Kuang +9 more
doaj +2 more sources
Ceramide and the membrane-fusion activity of LC3/GABARAP autophagy proteins [PDF]
Cellular and Molecular Life SciencesMacroautophagy is a cellular degradation process characterized by the formation of the double-membrane structure termed autophagosome (AP). The process of AP formation is not fully understood, but it is thought to happen through the combined action of ...
Yaiza R. Varela +8 more
doaj +2 more sources
Characterization of gene expression profiles in Alzheimer's disease and osteoarthritis: A bioinformatics study. [PDF]
PLoS ONEBackgroundAlzheimer's disease (AD) and Osteoarthritis (OA) have been shown to have a close association in previous studies, but the pathogenesis of both diseases are unclear. This study explores the potential common molecular mechanisms between AD and OA
Nian Liu +10 more
doaj +2 more sources
Diagnostics, 2021 Purpose: To investigate the association of autophagy-related gene expression with age-related macular degeneration (AMD). Methods: Patients with AMD were recruited for analysis by conjunctival impression cytology.
Chih-Wen Shu +5 more
doaj +1 more source