Results 41 to 50 of about 3,167 (176)
PLoS Pathogens, 2022 Host-pathogen dynamics are constantly at play during enteroviral infection. Coxsackievirus B (CVB) is a common juvenile enterovirus that infects multiple organs and drives inflammatory diseases including acute pancreatitis and myocarditis.
Savannah Sawaged +10 more
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GABARAPL1 is required for vIRF-1/NIX-mediated mitophagy.
, 2023 (A) Diagram of the mitophagy reporter, mito-mCE. The mCherry-EGFP tandem tag was fused to the mitochondrial targeting signal sequences (amino acids 1 to 33) of TOM20. A glycine-serine linker (L) was introduced between mCherry and EGFP.
Chang-Yong Choi (3597962) +2 more
core +1 more source
Identification of Hub Genes and Typing of Tuberculosis Infections Based on Autophagy-Related Genes
Polish Journal of Microbiology, 2023 Tuberculosis (TB) caused by Mycobacterium tuberculosis is one of the leading causes of morbidity and death in humans worldwide. Some autophagy genes associated with TB and some miRNAs regulating TB have been found, but the identification of autophagy ...
Sheng Yunfeng +3 more
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Heliyon, 2023 The number of people with neurodegenerative disease continues to increase every year. A new perspective is needed to overcome this disease. In this review, researchers collected information about dysfunctional energy in neurodegenerative diseases driven ...
Sri Widyarti +4 more
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GABARAPL1 protein and gabarapl1 mRNA staining in WT and GABARAP−/− mice.
, 2013 Immunohistochemical and in-situ hybridization analysis of WT and GABARAP−/− cortical mouse brain tissue with an anti-GABARAPL1 antibody (a, c–e) and an anti-sense gabarapl1 Dig-labelled probe (b).
Jianhua Zhang (6347) +7 more
core +1 more source
Regulation of Autophagy in Chick Skeletal Muscle: Effect of mTOR Inhibition
The Journal of Poultry Science, 2020 Autophagy in the skeletal muscle increases under catabolic conditions resulting in muscle atrophy. This study investigated the effect of inhibition of mechanistic target of rapamycin (mTOR) on autophagy in chick skeletal muscle.
Kazuki Nakashima, Aiko Ishida
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Cell Death and Disease, 2022 Channelling of glucose via glycogen, known as the glycogen shunt, may play an important role in the metabolism of brain tumours, especially in hypoxic conditions.
Christos E. Zois +16 more
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Cell Reports, 2023 Summary: The nucleolar scaffold protein NPM1 is a multifunctional regulator of cellular homeostasis, genome integrity, and stress response. NPM1 mutations, known as NPM1c variants promoting its aberrant cytoplasmic localization, are the most frequent ...
Hannah Mende +17 more
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vIRF-1 binds to GABARAPL1 in a manner different from cellular autophagy receptors.
, 2023 (A) The schematic structure of GABARAPL1 and its variants, VIRX, HPX, and G116A, are defective in binding to vIRF-1, LIR-containing proteins, and in phosphatidylethanolamine-lipidation, respectively.
Chang-Yong Choi (3597962) +2 more
core +1 more source
Oncology Reports, 2014 Autophagy is an evolutionarily conserved cellular process that degrades cytoplasmic materials through the lysosomal pathway. The deregulation of autophagy is associated with several diseases, particularly cancer. Hepatocellular carcinoma (HCC) is one of the most aggressive cancers with a poor prognosis.
Chao, Liu +4 more
openaire +3 more sources