Molecules, 2012 (E)-2-(benzo[d]thiazol-2-yl)-3-heteroarylacrylonitriles are described as a new class of selective inhibitors of acetylcholinesterase (AChE). The most potent compound in the series exhibited good AChE inhibitory activity (IC50 = 64 µM). Compound
Jorge Trilleras +6 more
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Galanthamin als AChE-Inhibitor : Beiträge zum rationalen Wirkstoffdesign [PDF]
von Christian PilgerPaderborn, Univ.-GH, Diss ...
Pilger, Christian
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Tacrine-allyl/propargylcysteine-benzothiazole trihybrids as potential anti-Alzheimer's drug candidates [PDF]
, 2016 The authors acknowledge the Portuguese Fundação para a Ciência e Tecnologia (FCT) for the project UID/QUI/00100/2013, postdoctoral fellowships (RSK and KC).
Cardoso, Sandra M +7 more
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Acetylcholinesterase inhibition by somes promising Brazilian medicinal plants
Brazilian Journal of BiologyA microplate assay and a thin-layer chromatography (TLC) "in situ" assay based on the Ellman assay was used to screen for acetylcholinesterase inhibitors from ethyl acetate and methanol extracts of Brazilian medicinal plants of families that, according ...
CM. Feitosa +4 more
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Representation and Treatment of Haemofilia in the general populaton in Macedonia [PDF]
, 2012 Introduction: Defects in blood coagulation can be congenital or acquired. Haemophilia belongs to the congenital (hereditary) coagulopathies.It is inherited recessively by a mutant gene located on the X-chromosome, therefore it affects only men. Women are
Velickova, Nevenka
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Rising CO2, Climate Change, and Public Health: Exploring the Links to Plant Biology [PDF]
, 2011 Background: Although the issue of anthropogenic climate forcing and public health is widely recognized, one fundamental aspect has remained underappreciated: the impact of climatic change on plant biology and the well-being of human systems.
Epstein, Paul Robert +2 more
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Comparative Analysis of Lycorine in Wild Plant and Callus Culture Samples of Hymenocallis littoralis by HPLC-UV Method [PDF]
, 2014 The Hymenocallis littoralis, an ornamental and medicinal plant, had been traditionally used for wound healing. In the present study, an analytical method using HPLC with ultraviolet detection was developed for the quantification of lycorine in the ...
Murugaiyah, Vikneswaran +3 more
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Portals to Wonderland: Health portals lead to confusing information about the effects of health care [PDF]
, 2005 Background The Internet offers a seemingly endless amount of health information of varying quality. Health portals, which provide entry points to quality-controlled collections of websites, have been hailed as a solution to this problem. The objective of
Claire Glenton +2 more
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Antioxidant, Anti-5-lipoxygenase and Antiacetylcholinesterase Activities of Essential Oils and Decoction Waters of Some Aromatic Plants [PDF]
, 2012 The scavenging of free radicals and superoxide anion, the inhibition of 5-lipoxygenase and the antiacetylcholinesterase activities of essential oils and decoction waters of eight aromatic plants (Dittrichia viscosa, Foeniculum vulgare, Origanum vulgare ...
Albano, Sílvia +5 more
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Synthesis of Precursors for the Oxidative Tandem Cyclization of Diphenols to Galanthamine Analogs
Molecules, 2002 Methods for the preparation of 4-bromo-5-[2-(4-hydroxybenzyl)benzyl]-2-methoxyphenol and 4-bromo-5-[4-(4-hydroxyphenyl)butyl]-2-methoxyphenol are described.
Ulrich Jordis, Matthias Treu
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