Results 11 to 20 of about 8,950,905 (317)
Galectin-9 in Gastroenterological Cancer
International Journal of Molecular Sciences, 2023 Immunochemotherapy has become popular in recent years. The detailed mechanisms of cancer immunity are being elucidated, and new developments are expected in the future.
A. Morishita +7 more
semanticscholar +4 more sources
Plasma Galectin-9 Concentrations in Normal and Diseased Condition [PDF]
Cellular Physiology and Biochemistry, 2018 Background/Aims: Galectin-9 is a soluble immune modulator with versatile functions, including a role as an immune checkpoint molecule. Therefore, the amount of galectin-9 in the blood may reflect an individual’s immunological balance.
Toshiro Niki +6 more
doaj +4 more sources
The regulating role of galectin-9 in immune cell populations. [PDF]
Front PharmacolGalectin-9 (gal-9) is a protein that belongs to the galectin family. Gal-9 is expressed in cells of the innate and adaptive immune system, including lymphocytes, dendritic cells, giant salivary cells, eosinophils and T cells, etc.
Cao Z, Leng P, Xu H, Li X.
europepmc +5 more sources
Galectin-9: A Suppressor of Atherosclerosis? [PDF]
Frontiers in Immunology, 2020 It is no longer controversial that atherosclerosis is a vascular wall chronic inflammatory disease mediated by cells of innate and adaptive immunity. Galectin-9 (Gal-9) seems to be a crucial regulator of T-cell immunity by inducing apoptosis in specific ...
Jian Yu +6 more
doaj +3 more sources
Interrogation of glioma immune microenvironment identifies a non-canonical role for microglial Galectin-9 in tumor cell adhesion and phagocytosis [PDF]
Frontiers in ImmunologyGlioma-associated microglia/macrophages (GAMs) have traditionally been described as immunosuppressive. However, within their highly heterogeneous repertoire, pro-phagocytic and cytotoxic subsets with anti-tumoral properties exist.
Pravesh Gupta +13 more
doaj +2 more sources
Brain and BehaviorPurpose The number of studies conducted on the role of neuroinflammation in the etiopathogenesis of bipolar disorder has been increasing in recent years.
Elcicek Selahaddin +6 more
doaj +2 more sources
Galectin-9 - ligand axis: an emerging therapeutic target for multiple myeloma. [PDF]
Front ImmunolGalectin-9 (Gal-9) is a tandem-repeat galectin with diverse roles in immune homeostasis, inflammation, malignancy, and autoimmune diseases. In cancer, Gal-9 displays variable expression patterns across different tumor types.
Shil RK, Mohammed NBB, Dimitroff CJ.
europepmc +2 more sources
T Cells Are Smad’ly in Love with Galectin-9 [PDF]
Immunity, 2014 In this issue of Immunity, Wu et al. (2014) report that galectin-9 is required for the formation and stability of iTreg cells. Galectin-9 interacts with CD44 in association with TGF-β receptors to drive both Foxp3 and galectin-9 expression in a positive ...
Cummings, Richard D.
core +3 more sources
PRDX2 induces tumor immune evasion by modulating the HDAC3-Galectin-9 axis in lung adenocarcinoma cells. [PDF]
J Transl MedPRDX2 is significantly expressed in various cancers and is associated with the proliferation of tumor cells. Nonetheless, the precise mechanism of PRDX2 in tumor immunity remains incompletely understood. This study aims to investigate the impact of PRDX2,
Dong Y +8 more
europepmc +2 more sources
Immunity, Inflammation and Disease, 2023 Background Galectin‐9 and myeloid‐derived suppressor cells (MDSCs) have an important role in tumors, but their clinical values in chronic lymphocytic leukemia (CLL) have not been fully elucidated.
Xierenguli Alimu +11 more
doaj +2 more sources