Results 31 to 40 of about 8,950,905 (317)
Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducing plasma cell apoptosis independently of Tim-3. [PDF]
PLoS ONE, 2013 Galectin-9 ameliorates various murine autoimmune disease models by regulating T cells and macrophages, although it is not known what role it may have in B cells.
Masahiro Moritoki +9 more
doaj +1 more source
Galectin‐9: a suppressor of food allergy? [PDF]
Allergy, 2012 The prevalence of food-induced allergy, which affects approximately 5% of children and 3–4% of adults, is on the rise. It is manifested in a variety of symptoms and disorders involving the gastrointestinal and respiratory tracts as well as skin (1). The pathogenesis of allergic diseases, such as allergic asthma, allergic dermatitis or food allergy is ...
Erna, Sziksz +2 more
openaire +2 more sources
Journal of Biomedical Science, 2020 Background Galectin-9 is a β-galactoside-binding protein with two carbohydrate recognition domains. Recent studies have revealed that galectin-9 regulates cellular biological reactions and plays a pivotal role in fibrosis.
Yu-An Hsu +7 more
doaj +1 more source
Galectin-1, -3 and -9 Expression and Clinical Significance in Squamous Cervical Cancer. [PDF]
PLoS ONE, 2015 Galectins are proteins that bind β-galactoside sugars and provide a new type of potential biomarkers and therapeutic targets in cancer. Galectin-1, -3 and -9 have become the focus of different research groups, but their expression and function in ...
Simone Punt +5 more
doaj +1 more source
Biomolecules, 2023 Gestational diabetes mellitus (GDM) is a common metabolic disease that occurs during pregnancy, with the placenta playing an important role in its pathophysiology. Currently, the role of galectin-9 in the development of GDM is unknown.
Aleksandra Pełech +7 more
doaj +1 more source
Galectin-9 Triggers Neutrophil-Mediated Anticancer Immunity [PDF]
Biomedicines, 2021 In earlier studies, galectin-9 (Gal-9) was identified as a multifaceted player in both adaptive and innate immunity. Further, Gal-9 had direct cytotoxic and tumor-selective activity towards cancer cell lines of various origins. In the current study, we identified that treatment with Gal-9 triggered pronounced membrane alterations in cancer cells ...
Natasha Ustyanovska Avtenyuk +8 more
openaire +4 more sources
Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection. [PDF]
, 2012 The S-type lectin galectin-9 binds to the negative regulatory molecule Tim-3 on T cells and induces their apoptotic deletion or functional inactivation.
Cheng, Y +59 more
core +1 more source
Galectin-9: A novel promoter of atherosclerosis progression
Atherosclerosis, 2022 Atherosclerosis is widely accepted to be an inflammatory disease driven by lipid accumulation and leukocyte recruitment. More recently, galectins, a family of β-galactoside binding proteins, have been shown to play a role in leukocyte recruitment among other immunomodulatory functions.
Krautter F. +15 more
openaire +5 more sources
Biomolecules, 2020 A previous study revealed that fucoidan inhibited mast cell degranulation through the upregulation of galectin-9 in blood. The purpose of this study is to elucidate its mechanism using ovalbumin (OVA) induced anaphylaxis model mice (BALB/c, Female, 5 ...
Masashi Mizuno +2 more
doaj +1 more source
Vaccines, 2021 During a specific milk fermentation process with Bifidobacterium breve C50 and Streptococcus thermophilus 065 (LactofidusTM), postbiotics with possible immunomodulatory properties are produced. We investigated the effects of this fermentation product (FP)
Veronica Ayechu-Muruzabal +9 more
doaj +1 more source