Results 151 to 160 of about 18,149 (205)
K. Seyrek, Max Richter, I. Lavrik
semanticscholar +1 more source
In EGFR‐mutant non‐small cell lung cancer, immune checkpoint inhibitors generally show limited efficacy. By integrating plasma proteomics and tumor immunohistochemistry, we identified biomarkers associated with durable clinical benefit and progression‐free survival following immunotherapy.
Min Seok Park +15 more
wiley +1 more source
Abstract Purpose To examine the presence of secretory autophagy and epithelial–mesenchymal transition (EMT) in the macular retinal pigment epithelium (RPE) of human cadaver eyes with different forms of age‐related macular degeneration (AMD). Methods Human cadaver macula samples representing dry and wet AMD, as well as age‐matched controls, were ...
Iswariyaraja Sridevi Gurubaran +3 more
wiley +1 more source
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley +1 more source
Human Milk Oligosaccharides as Essential Tools for Basic and Application Studies on Galectins
T. Urashima +3 more
semanticscholar +1 more source
Background and Purpose Inflammation plays a crucial role in the development and progression of numerous acute and chronic diseases such as myocardial infarction (MI) and heart failure. Targeting ADAM proteases, particularly ADAM10, holds promise for fine‐tuning inflammatory responses.
Erik Klapproth +16 more
wiley +1 more source
This study investigates the role of Sushi domain‐containing 2 (SUSD2) in pancreatic ductal adenocarcinoma (PDAC) and demonstrates that SUSD2 enhances both metastasis and primary tumor growth by promoting integrin β1–FAK signaling. SUSD2 interacts with integrin β1, enhancing adhesion to extracellular matrix (ECM) components such as collagen 1 and ...
Junjiro Yoshida +11 more
wiley +1 more source
Yuri D. Lobsanov, James M. Rini
openaire +2 more sources

