Results 11 to 20 of about 18,149 (205)
Current Biology, 2022 Banfer and Jacob introduce us to galectins - β-galactoside-binding lectins - and their range of functions in multicellular organisms.
Sebastian, Bänfer, Ralf, Jacob
semanticscholar +7 more sources
Galectins and galectin-mediated autophagy regulation: new insights into targeted cancer therapy
Biomarker Research, 2023 Galectins are animal lectins with specific affinity for galactosides via the conserved carbohydrate recognition domains. Increasing studies recently have identified critical roles of galectin family members in tumor progression.
Dan Liu, Hongtao Zhu, Chuanzhou Li
doaj +2 more sources
The role of galectins in virus infection - A systemic literature review
Journal of Microbiology, Immunology and Infection, 2020 Background: Galectins are β-Galactose binding lectins expressed in numerous cells and play multiple roles in various physiological and cellular functions. However, few information is available regarding the role of galectins in virus infections. Here, we
Wen-Hung Wang +8 more
doaj +2 more sources
Intracellular galectins sense cytosolically exposed glycans as danger and mediate cellular responses
Journal of Biomedical Science, 2021 Galectins are animal lectins that recognize carbohydrates and play important roles in maintaining cellular homeostasis. Recent studies have indicated that under a variety of challenges, intracellular galectins bind to host glycans displayed on damaged ...
Ming-Hsiang Hong +4 more
doaj +2 more sources
The Role of Galectins as Modulators of Metabolism and Inflammation
Mediators of Inflammation, 2018 Galectins are β-galcotosid-binding lectins. The function of galectins varies with their tissue-specific and subcellular location, and their binding to carbohydrates makes them key players in several intra- and extracellular processes where they bind to ...
Monica Fengsrud Brinchmann +2 more
doaj +2 more sources
Role of Human Galectins in Inflammation and Cancers Associated with Endometriosis
Biomolecules, 2020 Galectins are a family of β-galactoside-binding proteins that contribute to multiple cellular functions, including immune surveillance and apoptosis.
Brooke V. Hisrich +6 more
doaj +2 more sources
Utilization of Galectins by Pathogens for Infection
Frontiers in Immunology, 2020 Galectins are glycan-binding proteins which are expressed by many different cell types and secreted extracellularly. These molecules are well-known regulators of immune responses and involved in a broad range of cellular and pathophysiological functions.
Diyoly Ayona +5 more
doaj +2 more sources
Targeting Galectins With Glycomimetics
Frontiers in Chemistry, 2020 Among glycan-binding proteins, galectins, β-galactoside-binding lectins, exhibit relevant biological roles and are implicated in many diseases, such as cancer and inflammation.
Sara Bertuzzi +6 more
doaj +2 more sources
The role of galectins in immunity and infection
Nature reviews. Immunology, 2023 The galectin family consists of carbohydrate (glycan) binding proteins that are expressed by a wide variety of cells and bind to galactose-containing glycans.
Fu-Tong Liu, S. Stowell
semanticscholar +1 more source
Placental Galectins in Cancer: Why We Should Pay More Attention
Cells, 2023 The first studies suggesting that abnormal expression of galectins is associated with cancer were published more than 30 years ago. Today, the role of galectins in cancer is relatively well established.
Camille Fuselier +8 more
doaj +1 more source